The capture of CO2 by carboxylases is key to sustainable biocatalysis and a carbon-neutral
bio-economy, yet currently limited to few naturally existing enzymes. Here, we developed …

Having multiple rounds of translation of the same mRNA creates dynamic complexities
along with opportunities for regulation related to ribosome pausing and stalling at specific …

Genistin is one of the bioactive isoflavone glucosides found in legumes, which have great
nutraceutical and pharmaceutical significance. The market available isoflavones are …

Abstract One-carbon (C1) feedstocks can provide a vital link between cheap and
sustainable abiotic resources and microbial bioproduction. Soluble C1 substrates, methanol …

Ethylene glycol (EG) is an industrially important two-carbon diol used as a solvent,
antifreeze agent, and building block of polymers such as poly (ethylene terephthalate)(PET) …

The introduction of synthetic pathways into microbes often requires substantial modifications
of the host metabolism. Here, we present and discuss key experimental aspects required for …

D-glycerate is an attractive chemical for a wide variety of pharmaceutical, cosmetic,
biodegradable polymers, and other applications. Now several studies have been reported …

Using genome-wide mutant fitness assays in diverse bacteria, we identified novel oxidative
pathways for the catabolism of 2-deoxy-d-ribose and 2-deoxy-d-ribonate. We propose that …

Purines are abundant among organic nitrogen sources and have high nitrogen content.
Accordingly, microorganisms have evolved different pathways to catabolize purines and …

Bio-production of fuels and chemicals from lignocellulosic C5 sugars usually requires the
use of the pentose phosphate pathway (PPP) to produce pyruvate. Unfortunately, the …