Terahertz pulsed spectroscopy and imaging for pharmaceutical applications: A review

YC Shen - International journal of pharmaceutics, 2011 - Elsevier
The terahertz region of the electromagnetic spectrum spans the frequency range between
the infrared and the microwave. Traditionally the exploitation of this spectral region has been …

Process analytical technology tools for monitoring pharmaceutical unit operations: a control strategy for continuous process verification

EJ Kim, JH Kim, MS Kim, SH Jeong, DH Choi - Pharmaceutics, 2021 - mdpi.com
Various frameworks and methods, such as quality by design (QbD), real time release test
(RTRT), and continuous process verification (CPV), have been introduced to improve drug …

Terahertz spectroscopy: a powerful new tool for the chemical sciences?

AI McIntosh, B Yang, SM Goldup… - Chemical Society …, 2012 - pubs.rsc.org
Terahertz spectroscopy is only now beginning to make its transition from initial development
by physicists and engineers to broader use by chemists, materials scientists and biologists …

[HTML][HTML] Pharmaceutical application of tablet film coating

KS Seo, R Bajracharya, SH Lee, HK Han - Pharmaceutics, 2020 - mdpi.com
Tablet film coating is a common but critical process providing various functionalities to
tablets, thereby meeting diverse clinical needs and increasing the value of oral solid dosage …

First-Principles and Empirical Approaches to Predicting In Vitro Dissolution for Pharmaceutical Formulation and Process Development and for Product Release …

N Zaborenko, Z Shi, CC Corredor, BM Smith-Goettler… - The AAPS journal, 2019 - Springer
This manuscript represents the perspective of the Dissolution Working Group of the
International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) and …

Terahertz-based porosity measurement of pharmaceutical tablets: a tutorial

P Bawuah, D Markl, D Farrell, M Evans… - Journal of Infrared …, 2020 - Springer
Porosity, one of the important quality attributes of pharmaceutical tablets, directly affects the
mechanical properties, the mass transport and hence tablet disintegration, dissolution and …

In-vitro tomography and non-destructive imaging at depth of pharmaceutical solid dosage forms

JA Zeitler, LF Gladden - European Journal of Pharmaceutics and …, 2009 - Elsevier
Tomographic imaging techniques offer new prospects for a better understanding of the
quality, performance and release mechanisms of pharmaceutical solid dosage forms. It is …

Terahertz in-line sensor for direct coating thickness measurement of individual tablets during film coating in real-time

RK May, MJ Evans, S Zhong, I Warr, LF Gladden… - Journal of …, 2011 - Elsevier
We present a new in-line measurement technique to determine the coating thickness of
individual pharmaceutical tablets during film coating in a pan coating unit using pulsed …

Non-destructive quantification of pharmaceutical tablet coatings using terahertz pulsed imaging and optical coherence tomography

S Zhong, YC Shen, L Ho, RK May, JA Zeitler… - Optics and Lasers in …, 2011 - Elsevier
Optical coherence tomography (OCT) and terahertz pulsed imaging (TPI) are two powerful
techniques allowing high quality cross-sectional images from within scattering media to be …

Sensing and non-destructive testing applications of terahertz spectroscopy and imaging systems: State-of-the-art and state-of-the-practice

W Nsengiyumva, S Zhong, L Zheng… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
Terahertz (THz) technology has firmly established itself as an effective sensing and
nondestructive testing (NDT) technique for the detection of substances and physicochemical …