Tumor-associated macrophages: an effective player of the tumor microenvironment

U Basak, T Sarkar, S Mukherjee… - Frontiers in …, 2023 - frontiersin.org
Cancer progression is primarily caused by interactions between transformed cells and the
components of the tumor microenvironment (TME). TAMs (tumor-associated macrophages) …

Human circulating and tissue-resident memory CD8+ T cells

M Buggert, DA Price, LK Mackay, MR Betts - Nature Immunology, 2023 - nature.com
Our current knowledge of human memory CD8+ T cells is derived largely from studies of the
intravascular space. However, emerging data are starting to challenge some of the dogmas …

A guide to chemokines and their receptors

CE Hughes, RJB Nibbs - The FEBS journal, 2018 - Wiley Online Library
The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Guidelines for the use of flow cytometry and cell sorting in immunological studies*

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2017 - Wiley Online Library
From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …

Glucocorticoids—all-rounders tackling the versatile players of the immune system

C Strehl, L Ehlers, T Gaber, F Buttgereit - Frontiers in immunology, 2019 - frontiersin.org
Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Inflammatory and immune pathways in the pathogenesis of periodontal disease

A Cekici, A Kantarci, H Hasturk… - Periodontology …, 2014 - Wiley Online Library
The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …

SARS-CoV-2-specific T cells exhibit phenotypic features of helper function, lack of terminal differentiation, and high proliferation potential

J Neidleman, X Luo, J Frouard, G **e, G Gill… - Cell Reports …, 2020 - cell.com
Summary Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell
responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance …

Chemokines and chemokine receptors: positioning cells for host defense and immunity

JW Griffith, CL Sokol, AD Luster - Annual review of immunology, 2014 - annualreviews.org
Chemokines are chemo tactic cyto kines that control the migratory patterns and positioning
of all immune cells. Although chemokines were initially appreciated as important mediators …