[HTML][HTML] The role of BDNF in major depressive disorder, related clinical features, and antidepressant treatment: Insight from meta-analyses

D Cavaleri, F Moretti, A Bartoccetti, S Mauro… - Neuroscience & …, 2023 - Elsevier
The brain-derived neurotrophic factor (BDNF) has received considerable attention as a
potential biomarker of major depressive disorder (MDD) and antidepressant response. We …

Therapeutic use of psilocybin: Practical considerations for dosing and administration

CA MacCallum, LA Lo, CA Pistawka, JK Deol - Frontiers in Psychiatry, 2022 - frontiersin.org
The interest in psilocybin as a therapeutic approach has grown exponentially in recent
years. Despite increasing access, there remains a lack of practical guidance on the topic for …

[HTML][HTML] Hyperactive neuronal autophagy depletes BDNF and impairs adult hippocampal neurogenesis in a corticosterone-induced mouse model of depression

K Zhang, F Wang, M Zhai, M He, Y Hu, L Feng, Y Li… - Theranostics, 2023 - ncbi.nlm.nih.gov
Background: Depression is a mental disorder that poses a serious threat to human health.
Adult hippocampal neurogenesis (AHN) is closely associated with the efficacy of …

N6-methyladenosine and neurological diseases

N Zhang, C Ding, Y Zuo, Y Peng, L Zuo - Molecular neurobiology, 2022 - Springer
Abstract N6-methyladenosine (m6A) is a dynamic reversible methylation modification of the
adenosine N6 position and is the most common chemical epigenetic modification among …

[HTML][HTML] The brain-gut-microbiota interplay in depression: A key to design innovative therapeutic approaches

A Varesi, LIM Campagnoli, S Chirumbolo… - Pharmacological …, 2023 - Elsevier
Depression is the most prevalent mental disorder in the world associated with huge socio-
economic consequences. While depressive-related symptoms are well known, the …

The role of brain-derived neurotrophic factor (BDNF) in diagnosis and treatment of epilepsy, depression, schizophrenia, anorexia nervosa and Alzheimer's disease as …

A Gliwińska, J Czubilińska-Łada, G Więckiewicz… - Brain Sciences, 2023 - mdpi.com
Brain-derived neurotrophic factor (BDNF) belongs to the family of neurotrophins, which are
growth factors with trophic effects on neurons. BDNF is the most widely distributed …

BDNF impact on biological markers of depression—role of physical exercise and training

E Murawska-Ciałowicz, M Wiatr, M Ciałowicz… - International journal of …, 2021 - mdpi.com
Depression is the most common and devastating psychiatric disorder in the world. Its
symptoms, especially during the pandemic, are observed in all age groups. Exercise training …

[HTML][HTML] Omega-3 polyunsaturated fatty acids in depression

A Serefko, ME Jach, M Pietraszuk, M Świąder… - International Journal of …, 2024 - mdpi.com
Omega-3 polyunsaturated fatty acids have received considerable attention in the field of
mental health, in particular regarding the treatment of depression. This review presents an …

Effect of short-term, high-dose probiotic supplementation on cognition, related brain functions and BDNF in patients with depression: a secondary analysis of a …

E Schneider, JPK Doll, N Schweinfurth… - Journal of Psychiatry and …, 2023 - jpn.ca
Background: In major depressive disorder (MDD), cognitive dysfunctions strongly contribute
to functional impairments but are barely addressed in current therapies. Novel treatment …

[HTML][HTML] Crosstalk among NLRP3 inflammasome, ETBR signaling, and miRNAs in stress-induced depression-like behavior: a modulatory role for SGLT2 inhibitors

RN Muhammad, LA Ahmed, RMA Salam, KA Ahmed… - …, 2021 - Elsevier
Depression is an overwhelming health concern, and many patients fail to optimally respond
to available standard therapies. Neuroplasticity and blood–brain barrier (BBB) integrity are …