Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …
Cyclodextrins as chiral selectors in capillary electrophoresis: Recent trends in mechanistic studies
B Chankvetadze, GKE Scriba - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
In the present review the potential of capillary electrophoresis for a better understanding of
the fine structural mechanisms of noncovalent interactions and enantioselective …
the fine structural mechanisms of noncovalent interactions and enantioselective …
New trends in the quality control of enantiomeric drugs: quality by design-compliant development of chiral capillary electrophoresis methods
Capillary electrophoresis (CE) is a potent method for analyzing chiral substances and is
commonly used in the enantioseparation and chiral purity control of pharmaceuticals from …
commonly used in the enantioseparation and chiral purity control of pharmaceuticals from …
[HTML][HTML] Recent developments in molecular modeling tools and applications related to pharmaceutical and biomedical research
In modern pharmaceutical and biomedical research, molecular modeling represents a
useful tool to explore processes and their mechanistic bases at the molecular level …
useful tool to explore processes and their mechanistic bases at the molecular level …
[HTML][HTML] Isothermal titration calorimetry and molecular modeling study of the complex formation of daclatasvir by γ-cyclodextrin and trimethyl-β-cyclodextrin
The complex formation between daclatasvir and γ-CD or heptakis (2, 3, 6-tri-O-methyl)-β-CD
(TM-β-CD) was studied by isothermal titration calorimetry and molecular modeling. Both …
(TM-β-CD) was studied by isothermal titration calorimetry and molecular modeling. Both …
The potential of the use of deep eutectic solvents and amino acid-based ionic liquids to enhance the chiral discrimination ability of different chiral selectors in capillary …
The effect of the combined use of amino acid-based ionic liquids (AAILs) and deep eutectic
solvents (DESs) with either cyclodextrin-(CD) or cyclofructan-(CF) based chiral selectors for …
solvents (DESs) with either cyclodextrin-(CD) or cyclofructan-(CF) based chiral selectors for …
Enhancement of chiral drugs separation by a novel adjustable gravity mediated capillary electrophoresis combined with sulfonic propyl ether β-CD polymer
Y Nan, P Zheng, M Cheng, R Zhao, H Jia, Q Liang… - Analytica Chimica …, 2023 - Elsevier
A water-soluble negative sulfonic propyl ether β-CD polymer (SPE-β-CDP) to be used as
chiral selector in capillary electrophoresis (CE) was polymerized. The sulfonic substitution …
chiral selector in capillary electrophoresis (CE) was polymerized. The sulfonic substitution …
Tridentate xanthene-based hydrazone ligands and their mononuclear transition metal complexes: synthesis, anti-malarial, antimicrobial and molecular docking …
In the search of potential multi-target medicinal agents, new NOO-tridentate hydrazone
ligands (H2L1–H2L4)(1–4) and their transition metal (II) complexes (5–20) were synthesized …
ligands (H2L1–H2L4)(1–4) and their transition metal (II) complexes (5–20) were synthesized …
A cooperation tale of biomolecules and nanomaterials in nanoscale chiral sensing and separation
The cooperation relation between biomolecules and nanomaterials makes up a beautiful
tale about nanoscale chiral sensing and separation. Biomolecules are considered a …
tale about nanoscale chiral sensing and separation. Biomolecules are considered a …
Carboxymethylated maltodextrin as a chiral selector for the separation of some basic drug enantiomers using capillary electrophoresis
In this work, carboxymethylated maltodextrin (Cm-MD) was successfully synthesized as an
efficient anionic chiral selector and applied for the enantiomer separation of some basic …
efficient anionic chiral selector and applied for the enantiomer separation of some basic …