Modern classification of the family of human small heat shock proteins (the so-called HSPB)
is presented, and the structure and properties of three members of this family are analyzed …

Hsp27, αB-crystallin and HSP22 are ubiquitous small heat shock proteins (sHsp) whose
expression is induced in response to a wide variety of unfavorable physiological and …

To obtain an inventory of all human genes that code for α-crystallin–related small heat shock
proteins (sHsps), the databases available from the public International Human Genome …

Distal hereditary motor neuropathies are pure motor disorders of the peripheral nervous
system resulting in severe atrophy and wasting of distal limb muscles. In two pedigrees with …

Actin and small heat shock proteins (sHsps) are ubiquitous and multifaceted proteins that
exist in 2 reversible forms, monomers and multimers, ie, the microfilament of the …

Dendritic cells (DCs) are specialized APCs that can be activated upon pathogen recognition
as well as recognition of endogenous ligands, which are released during inflammation and …

Myoblasts respond to growth factor deprivation either by differentiating into multinucleated
myotubes or by undergoing apoptosis; hence, the acquisition of apoptosis resistance by …

Small MW heat shock proteins (ie sHSPs~ 15–30 kDa) share significant sequence similarity
within the “alpha-crystallin domain” but exhibit different patterns of gene expression …

The cellular response to cancer-induced stress is one of the major aspects regulating cancer
development and progression. The Heat Shock Protein B8 (HSPB8) is a small chaperone …

Skeletal muscle and the nervous system depend on efficient protein quality control, and they
express chaperones and cochaperones at high levels to maintain protein homeostasis …