Melt extrusion with poorly soluble drugs
Melt extrusion (ME) over recent years has found widespread application as a viable drug
delivery option in the drug development process. ME applications include taste masking …
delivery option in the drug development process. ME applications include taste masking …
Characterization of amorphous solid dispersions
The study of amorphous solid dispersions (ASDs) is currently one of the most exciting areas
in pharmaceutics. Research has shown that ASDs offer unique advantages in improving the …
in pharmaceutics. Research has shown that ASDs offer unique advantages in improving the …
Measuring material softening with nanoscale spatial resolution using heated silicon probes
Many techniques exist for measuring the temperature dependence of material properties. A
common technique for measuring chemical and thermodynamic properties is differential …
common technique for measuring chemical and thermodynamic properties is differential …
In vitro drug release from acetylated high amylose starch-zein films for oral colon-specific drug delivery
This study describes the preparation of free films of zein with and without acetylated high
amylose maize starch (HAS) and their corresponding coated tablets as a novel approach to …
amylose maize starch (HAS) and their corresponding coated tablets as a novel approach to …
A spectroscopic and thermal investigation into the relationship between composition, secondary structure and physical characteristics of electrospun zein nanofibers
YH Wang, M Zhao, SA Barker, PS Belton… - Materials Science and …, 2019 - Elsevier
Electrospun zein nanofibers have attracted interest as drug delivery systems due to their
propensity for controlled drug release, flexible structure and low toxicity. However …
propensity for controlled drug release, flexible structure and low toxicity. However …
Fast-Scan DSC and its role in pharmaceutical physical form characterisation and selection
JL Ford, TE Mann - Advanced Drug Delivery Reviews, 2012 - Elsevier
Conventional rate Differential Scanning Calorimetry (DSC) has been used for many years as
a tool in the analysis of pharmaceutical materials. In recent years an extension of the …
a tool in the analysis of pharmaceutical materials. In recent years an extension of the …
Solid dispersions for oral administration: an overview of the methods for their preparation
F Hallouard, L Mehenni… - Current …, 2016 - ingentaconnect.com
Oral drug delivery remains the most physiological and therefore the most preferred, simplest
and easiest administration route. Nevertheless, a multitude of potentially clinically important …
and easiest administration route. Nevertheless, a multitude of potentially clinically important …
Identification of phase separation in solid dispersions of itraconazole and Eudragit® E100 using microthermal analysis
K Six, J Murphy, I Weuts, DQM Craig, G Verreck… - Pharmaceutical …, 2003 - Springer
Purpose. To evaluate the phase separation in itraconazole/Eudragit® E100 solid
dispersions prepared by hot-stage extrusion. Methods. Extrudates were prepared using a …
dispersions prepared by hot-stage extrusion. Methods. Extrudates were prepared using a …
Microenvironmental pH-modified solid dispersions to enhance the dissolution and bioavailability of poorly water-soluble weakly basic GT0918, a develo** anti …
M Yang, S He, Y Fan, Y Wang, Z Ge, L Shan… - International journal of …, 2014 - Elsevier
The aim of the present work was to design a pH-modified solid dispersion (pH M-SD) that
can improve the dissolution and bioavailability of poorly water-soluble weakly basic …
can improve the dissolution and bioavailability of poorly water-soluble weakly basic …
Spatially resolved thermal desorption/ionization coupled with mass spectrometry
(57) ABSTRACT A system and method for Sub-micron analysis of a chemical composition of
a specimen are described. The method includes providing a specimen for evaluation and a …
a specimen are described. The method includes providing a specimen for evaluation and a …