Development of human respiratory airway models: A review

K Ahookhosh, O Pourmehran, H Aminfar… - European Journal of …, 2020 - Elsevier
Pulmonary drug delivery has gained great interest as an important subject of research over
the past decades given the lung diseases which are affecting millions of people suffer from …

Experimental methods for flow and aerosol measurements in human airways and their replicas

F Lizal, J Jedelsky, K Morgan, K Bauer, J Llop… - European Journal of …, 2018 - Elsevier
Recent developments in the prediction of local aerosol deposition in human lungs are driven
by the fast development of computational simulations. Although such simulations provide …

Can CFD establish a connection to a milder COVID-19 disease in younger people? Aerosol deposition in lungs of different age groups based on Lagrangian particle …

J Wedel, P Steinmann, M Štrakl, M Hriberšek… - Computational …, 2021 - Springer
To respond to the ongoing pandemic of SARS-CoV-2, this contribution deals with recently
highlighted COVID-19 transmission through respiratory droplets in form of aerosols. Unlike …

Air–liquid interactions in a pressure-swirl spray

J Jedelsky, M Maly, NP Del Corral, G Wigley… - International Journal of …, 2018 - Elsevier
The energy transfer between a liquid hollow cone spray and the surrounding air has been
studied using both imaging and phase-Doppler techniques. The spray was produced by a …

The effect of oral and nasal breathing on the deposition of inhaled particles in upper and tracheobronchial airways

F Lizal, J Elcner, J Jedelsky, M Maly, M Jicha… - Journal of aerosol …, 2020 - Elsevier
The inhalation route has a substantial influence on the fate of inhaled particles. An outbreak
of infectious diseases such as COVID-19, influenza or tuberculosis depends on the site of …

Numerical investigation of inspiratory airflow in a realistic model of the human tracheobronchial airways and a comparison with experimental results

J Elcner, F Lizal, J Jedelsky, M Jicha… - … and modeling in …, 2016 - Springer
In this article, the results of numerical simulations using computational fluid dynamics (CFD)
and a comparison with experiments performed with phase Doppler anemometry are …

Computational evaluation of drug delivery in human respiratory tract under realistic inhalation

A Tiwari, A Jain, AR Paul, SC Saha - Physics of Fluids, 2021 - pubs.aip.org
In recent years, pulmonary diseases have posed severe health problems because of
increasing air pollution. Some of the promising drug delivery devices for administering the …

[HTML][HTML] A critical analysis of the CFD-DEM simulation of pharmaceutical aerosols deposition in upper intra-thoracic airways: Considerations on air flow

GH Spasov, R Rossi, A Vanossi, C Cottini… - Computers in Biology …, 2024 - Elsevier
A well-corroborated numerical methodology ensuring reproducibility in the modeling of
pharmaceutical aerosols deposition in the respiratory system via CFD-DEM simulations …

Time-resolved characteristics of oscillatory particle-laden air flow in a realistic human airway model

J Jedelsky, F Lizal, M Jicha - European Journal of Mechanics-B/Fluids, 2024 - Elsevier
Human airways represent a complex flow system with a spatially and temporally variable
character of air flow during respiration. In this paper, we experimentally studied the …

3D phase contrast MRI in models of human airways: Validation of computational fluid dynamics simulations of steady inspiratory flow

GJ Collier, M Kim, Y Chung… - Journal of Magnetic …, 2018 - Wiley Online Library
Background Knowledge of airflow patterns in the large airways is of interest in obstructive
airways disease and in the development of inhaled therapies. Computational fluid dynamics …