The Wnt signal transduction pathway has essential roles in the formation of the primary body
axis during development, cellular differentiation and tissue homeostasis. This animal …

Horizontal gene transfer (HGT) is the sharing of genetic material between organisms that are
not in a parent–offspring relationship. HGT is a widely recognized mechanism for adaptation …

Animal genomes show networks of deeply conserved gene linkages whose phylogenetic
scope and chromosomal context remain unclear. Here, we report chromosome-scale …

INTRODUCTION The cnidarian polyp Hydra undergoes continual self-renewal and is
capable of whole-body regeneration from a small piece of tissue. The stem cell populations …

Background The interplay between hosts and their associated microbiome is now
recognized as a fundamental basis of the ecology, evolution, and development of both …

The results of many medical measurements are directly or indirectly influenced by the
autonomic nervous system (ANS). For example pupil size or heart rate may demonstrate …

The sea lamprey (Petromyzon marinus) serves as a comparative model for reconstructing
vertebrate evolution. To enable more informed analyses, we developed a new assembly of …

The most diverse marine ecosystems, coral reefs, depend upon a functional symbiosis
between a cnidarian animal host (the coral) and intracellular photosynthetic dinoflagellate …

There is currently little information about the evolution of gene clusters, genome
architectures and karyotypes in early branching animals. Slowly evolving anthozoan …

Completion of genome sequences for many organisms allows a reasonably complete
definition of the complement of extracellular matrix (ECM) proteins. In mammals this “core …