Recent advances in our understanding of the mechanisms of late lung development and bronchopulmonary dysplasia

DE Surate Solaligue… - … of Physiology-Lung …, 2017‏ - journals.physiology.org
The objective of lung development is to generate an organ of gas exchange that provides
both a thin gas diffusion barrier and a large gas diffusion surface area, which concomitantly …

Recent advances in the pathogenesis of BPD

RE Morty - Seminars in perinatology, 2018‏ - Elsevier
Bronchopulmonary dysplasia (BPD) continues to be one of the most common complications
of preterm birth and is characterized histopathologically by impaired lung alveolarization …

[HTML][HTML] Extracellular vesicles and their miRNA content in amniotic and tracheal fluids of fetuses with severe congenital diaphragmatic hernia undergoing fetal …

I Fabietti, T Nardi, C Favero, L Dioni, L Cantone… - Cells, 2021‏ - mdpi.com
Infants with congenital diaphragmatic hernia (CDH) are at high risk of postnatal mortality due
to lung hypoplasia and arterial pulmonary hypertension. In severe cases, prenatal …

Pathomechanisms of congenital cystic lung diseases: focus on congenital cystic adenomatoid malformation and pleuropulmonary blastoma

O Boucherat, L Jeannotte, A Hadchouel… - Paediatric respiratory …, 2016‏ - Elsevier
It is well established that a number of birth defects are associated with improper formation of
the respiratory tract. Important progress has been made in the identification of components …

Epigenetic regulation and its therapeutic potential in pulmonary hypertension

Y Wang, L Yan, Z Zhang, E Prado, L Fu… - Frontiers in …, 2018‏ - frontiersin.org
Recent advances in epigenetics have made a tremendous impact on our knowledge of
biological phenomena and the environmental stressors on complex diseases …

[HTML][HTML] miR-483-5p plays a protective role in chronic obstructive pulmonary disease

Z Shen, W Tang, J Guo, S Sun - … journal of molecular …, 2017‏ - spandidos-publications.com
Altered microRNA (miRNA or miR) expression has been reported in chronic obstructive
pulmonary disease (COPD). The present study aimed to identify the involvement of miRNAs …

MiR-205 serves as a prognostic factor and suppresses proliferation and invasion by targeting insulin-like growth factor receptor 1 in human cervical cancer

H Pang, X Yue - Tumor Biology, 2017‏ - journals.sagepub.com
MicroRNAs are a kind of small and non-coding RNAs, which have been demonstrated to
play an important role in the progression of human cervical cancer. Here, we found that the …

Mechanism of lncRNA H19 in regulating pulmonary injury in hyperoxia-induced bronchopulmonary dysplasia newborn mice

L Zhang, P Wang, Y Shen, T Huang… - American Journal of …, 2022‏ - thieme-connect.com
Objective Bronchopulmonary dysplasia (BPD) is a pulmonary injury related to inflammation
and is a major cause of premature infant death. Long noncoding RNAs (lncRNAs) are …

Decreased expression of miR-33 in fetal lungs of nitrofen-induced congenital diaphragmatic hernia rat model

S Zhu, Q He, R Zhang, Y Wang, W Zhong, H **a… - Journal of Pediatric …, 2016‏ - Elsevier
Background The pathogenesis of congenital diaphragmatic hernia (CDH) and the causes of
pulmonary hypoplasia and hypertension remain unclear. miRNAs have been identified to …

The effects of tracheal occlusion on Wnt signaling in a rabbit model of congenital diaphragmatic hernia

M Mudri, SA Smith, C Vanderboor, J Davidson… - Journal of Pediatric …, 2019‏ - Elsevier
Purpose Tracheal occlusion (TO) reverses pulmonary hypoplasia (PH) in congenital
diaphragmatic hernia (CDH), but its mechanism of action remains poorly understood. Wnt …