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Emerging roles and functional mechanisms of PIWI-interacting RNAs
X Wang, A Ramat, M Simonelig, MF Liu - Nature Reviews Molecular …, 2023 - nature.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …
PIWI-interacting RNAs: small RNAs with big functions
In animals, PIWI-interacting RNAs (piRNAs) of 21–35 nucleotides in length silence
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
piRNA-guided genome defense: from biogenesis to silencing
PIWI-interacting RNAs (piRNAs) and their associated PIWI clade Argonaute proteins
constitute the core of the piRNA pathway. In gonadal cells, this conserved pathway is crucial …
constitute the core of the piRNA pathway. In gonadal cells, this conserved pathway is crucial …
The expanding world of small RNAs in plants
Plant genomes encode various small RNAs that function in distinct, yet overlap**, genetic
and epigenetic silencing pathways. However, the abundance and diversity of small-RNA …
and epigenetic silencing pathways. However, the abundance and diversity of small-RNA …
Transcriptional termination in mammals: Stop** the RNA polymerase II juggernaut
NJ Proudfoot - Science, 2016 - science.org
BACKGROUND Genes correspond to single transcription units, starting from the promoter
and ending at the terminator. Terminating gene transcription is directly coupled to mRNA …
and ending at the terminator. Terminating gene transcription is directly coupled to mRNA …
One loop to rule them all: the **-pong cycle and piRNA-guided silencing
The PIWI-interacting RNA (piRNA) pathway is a conserved defense mechanism that protects
the genetic information of animal germ cells from the deleterious effects of molecular …
the genetic information of animal germ cells from the deleterious effects of molecular …
PIWI-interacting RNA: its biogenesis and functions
PIWI-interacting RNAs (piRNAs) are a class of small RNAs that are 24–31 nucleotides in
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
length. They associate with PIWI proteins, which constitute a germline-specific subclade of …
RISC assembly: Coordination between small RNAs and Argonaute proteins
H Kobayashi, Y Tomari - Biochimica et Biophysica Acta (BBA)-Gene …, 2016 - Elsevier
Non-coding RNAs generally form ribonucleoprotein (RNP) complexes with their partner
proteins to exert their functions. Small RNAs, including microRNAs, small interfering RNAs …
proteins to exert their functions. Small RNAs, including microRNAs, small interfering RNAs …
piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production
PIWI-interacting RNAs (piRNAs) protect the animal germ line by silencing transposons.
Primary piRNAs, generated from transcripts of genomic transposon “junkyards”(piRNA …
Primary piRNAs, generated from transcripts of genomic transposon “junkyards”(piRNA …
piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis
In animal gonads, PIWI-clade Argonaute proteins repress transposons sequence-
specifically via bound Piwi-interacting RNAs (piRNAs). These are processed from single …
specifically via bound Piwi-interacting RNAs (piRNAs). These are processed from single …