Oxidative stress and male infertility: current knowledge of pathophysiology and role of antioxidant therapy in disease management
Infertility is a global health problem involving about 15% of couples. Approximately half of
the infertility cases are related to male factors. The oxidative stress, which refers to an …
the infertility cases are related to male factors. The oxidative stress, which refers to an …
[HTML][HTML] Impact of oxidative stress on male and female germ cells: implications for fertility
RJ Aitken - Reproduction, 2020 - rep.bioscientifica.com
Male and female germ lines are vulnerable to oxidative stress. In spermatozoa, such stress
triggers a lipid peroxidation cascade that culminates in the generation of electrophilic lipid …
triggers a lipid peroxidation cascade that culminates in the generation of electrophilic lipid …
Efficient near infrared light triggered nitric oxide release nanocomposites for sensitizing mild photothermal therapy
Mild photothermal therapy (PTT), as a new anticancer therapeutic strategy, faces big
challenges of limited therapeutic accuracy and side‐effects due to uneven heat distribution …
challenges of limited therapeutic accuracy and side‐effects due to uneven heat distribution …
Causes, effects and molecular mechanisms of testicular heat stress
D Durairajanayagam, A Agarwal, C Ong - Reproductive biomedicine online, 2015 - Elsevier
The process of spermatogenesis is temperature-dependent and occurs optimally at
temperatures slightly lower than that of the body. Adequate thermoregulation is imperative to …
temperatures slightly lower than that of the body. Adequate thermoregulation is imperative to …
Autophagy: a multifaceted player in the fate of sperm
M Wang, L Zeng, P Su, L Ma, M Zhang… - Human Reproduction …, 2022 - academic.oup.com
BACKGROUND Autophagy is an intracellular catabolic process of degrading and recycling
proteins and organelles to modulate various physiological and pathological events …
proteins and organelles to modulate various physiological and pathological events …
[HTML][HTML] Polystyrene microplastics induce mitochondrial damage in mouse GC-2 cells
T Liu, B Hou, Z Wang, Y Yang - Ecotoxicology and Environmental Safety, 2022 - Elsevier
Microplastics are widely distributed, such as oceans, rivers and the atmosphere, with many
opportunities for human exposure and potential health risks. Polystyrene microplastic (PS …
opportunities for human exposure and potential health risks. Polystyrene microplastic (PS …
[HTML][HTML] Oxidative stress-induced apoptosis and autophagy: Balancing the contrary forces in spermatogenesis
Spermatogenesis is a complex process in the testis and is a cornerstone of male infertility.
The abundance of unsaturated fatty acid and high cell division rate make male germs cells …
The abundance of unsaturated fatty acid and high cell division rate make male germs cells …
Heat shock response and autophagy—cooperation and control
Protein quality control (proteostasis) depends on constant protein degradation and
resynthesis, and is essential for proper homeostasis in systems from single cells to whole …
resynthesis, and is essential for proper homeostasis in systems from single cells to whole …
Diet-induced obesity impairs spermatogenesis: A potential role for autophagy
Y Mu, W Yan, T Yin, Y Zhang, J Li, J Yang - Scientific reports, 2017 - nature.com
Autophagy is an evolutionarily conserved process that plays a crucial role in maintaining a
series of cellular functions. It has been found that autophagy is closely involved in the …
series of cellular functions. It has been found that autophagy is closely involved in the …
Mechanism of inflammatory associated impairment of sperm function, spermatogenesis and steroidogenesis
H Hasan, S Bhushan, M Fijak… - Frontiers in Endocrinology, 2022 - frontiersin.org
Infection and inflammation are relevant entities of male reproductive disorders that can lead
to sub-/infertility. Associated damage of the testis of affected men and in rodent models …
to sub-/infertility. Associated damage of the testis of affected men and in rodent models …