Adipose tissue depots can exist in close association with other organs, where they assume
diverse, often non-traditional functions. In stem cell-rich skin, bone marrow, and mammary …

The development of the mammary gland is unique: the final stages of development occur
postnatally at puberty under the influence of hormonal cues. Furthermore, during the life of …

Introduction The immune system plays a major role in cancer progression. In solid tumors, 5-
40% of the tumor mass consists of tumor-associated macrophages (TAMs) and there is …

Macrophages are diverse immune cells that reside in all tissues. Although macrophages
have been implicated in mammary-gland function, their diversity has not been fully …

INTRODUCTION The stem cell niche plays a crucial role in regulating key stem cell
properties, including self-renewal, differentiation, and cell fate change. Although stem cell …

Macrophages are involved in immune defense, organogenesis and tissue homeostasis.
Macrophages contribute to the different phases of mammary gland remodeling during …

Several studies have made strong efforts to understand how age and parity modulate the
risk of breast cancer. A holistic understanding of the dynamic regulation of the …

The pace of repair declines with age and, while exposure to a young circulation can
rejuvenate fracture repair, the cell types and factors responsible for rejuvenation are …

Adipocytes undergo pronounced changes in size and behavior to support diverse tissue
functions, but the mechanisms that control these changes are not well understood …

Cell death occurs when a pathogen invades a host organism or the organism is subjected to
sterile injury. Thus, cell death is often closely associated with the induction of an immune …