The use of biomaterials in regenerative medicine has expanded to treat various disorders
caused by trauma or disease in orthopedics and dentistry. However, the treatment of large …

Bone cancer is usually a metastatic disease, affecting people of all ages. Its effective therapy
requires a targeted drug administration locally at the cancer site so that the surrounding …

Critical-sized maxillofacial bone defects have been a tough clinical challenge considering
their requirements for functional and structural repair. In this study, an injectable in-situ …

Nanoparticles can regulate the rheological behavior of polymers during three-dimensional
(3D) printing. To overcome the poor molding performance of pure sodium alginate (SA), the …

Cartilage repair after a trauma or a degenerative disease like osteoarthritis (OA) continues to
be a big challenge in current medicine due to the limited self-regenerative capacity of the …

Despite considerable advances in artificial bone tissues, the absence of neural network
reconstruction in their design often leads to delayed or ineffective bone healing. Hence, we …

As an endogenous signaling molecule, metal ions not only play an important role in the
physiological development of the maxillofacial bone, but also can improve the repair of …

Bone regeneration in a diabetic environment remains a clinical challenge because of the
proinflammatory microenvironment and malfunction of osteogenesis. Traditional therapy for …

Bone cement is widely used in clinical with optimistic filling and mechanical properties.
However, the setting time of bone cement is difficult to accurately control, and the existing …

Polyetheretherketone (PEEK) is a frequently utilized orthopedic implant material in clinical
settings. However, the adverse inflammatory and immunological reactions due to the PEEK …