The falling cost of genome sequencing is having a marked impact on the research
community with respect to which genomes are sequenced and how and where they are …

Simple Summary Due to the development of high-throughput sequencing technologies,
computational genome annotation of sequences has become one of the principal research …

We evaluated 25 protocol variants of 14 independent computational methods for exon
identification, transcript reconstruction and expression-level quantification from RNA-seq …

We describe a new 'reference annotation based transcript assembly'problem for RNA-Seq
data that involves assembling novel transcripts in the context of an existing annotation. This …

The ENCODE Project has generated a wealth of experimental information map** diverse
chromatin properties in several human cell lines. Although each such data track is …

Genetic differences between Arabidopsis thaliana accessions underlie the plant's extensive
phenotypic variation, and until now these have been interpreted largely in the context of the …

Lead (Pb) is a primary toxic heavy metal (HM) which present throughout the entire
ecosystem. Some commonly observed challenges in HM (Pb) prediction using artificial …

Recent advances in sequencing and informatic technologies have led to a deluge of publicly
available genomic data. While it is now relatively easy to sequence, assemble, and identify …

Cancer is an important reason of death worldwide. Traditional cytotoxic therapies, such as
radiation and chemotherapy, are expensive and cause severe side effects. Currently, design …

The prediction of protein coding genes is an important step in the annotation of newly
sequenced and assembled genomes. AUGUSTUS is one of the most accurate tools for …