Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a
significant assembly motif for the development of new drug entities. Quinoline and its …

Quinoline or 1-aza-naphthalene is a weak tertiary base. Quinoline ring has been found to
possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti …

This review summarizes the importance and recent discoveries of the use of adamantane
derivatives in Medicinal Chemistry. We have organized the article in 4 sections: 1) …

We identified two new-type cannabimimetic quinolinyl carboxylates, quinolin-8-yl 1-pentyl-(1
H-indole)-3-carboxylate (QUPIC, 1) and quinolin-8-yl 1-(cyclohexylmethyl)-1 H-indole-3 …

The endocannabinoid system is represented by a group of neuromodulatory lipids and their
receptors that are involved in a variety of physiological and pathological conditions. The …

The cannabinoid receptor type 2 (CB2) is a class A GPCR that was cloned in 1993 while
looking for an alternative receptor that could explain the pharmacological properties of Δ9 …

The cannabinoid receptor type 1 (CB1R) is pivotal within the endocannabinoid system
regulating various signaling cascades with effects in appetite regulation, pain perception …

The 1, 8‐naphthyridine group of compounds have gained special attention of researchers
on account of their demonstrating a variety of interesting biological activities. A wide range of …

Quinoline-based small molecules have been explored and being developed as anti-
inflammatory agents targeting several pharmacological targets namely Phosphodiesterase 4 …

Quinolones are among the most common frameworks present in the bioactive molecules
and hence represent an attractive starting point for the design of combinatorial libraries …