Engineering of calcium overload for state-of-the-art tumor therapy
X Liu, H Hu, J Chen, Y Li, Y Cheng, H Wei… - Chemical Engineering …, 2024 - Elsevier
As a crucial messenger, calcium ion (Ca 2+) is essential for regulating diverse biological
processes. Once the Ca 2+ content remarkably exceeds the cellular tolerant capacity …
processes. Once the Ca 2+ content remarkably exceeds the cellular tolerant capacity …
Design and advances in antioxidant hydrogels for ROS-induced oxidative disease
Y **a, X Li, F Huang, Y Wu, J Liu, J Liu - Acta Biomaterialia, 2025 - Elsevier
Reactive oxygen species (ROS) play a crucial role in human physiological processes, but
oxidative stress caused by excessive ROS may lead to a variety of acute and chronic …
oxidative stress caused by excessive ROS may lead to a variety of acute and chronic …
In situ enzymatic peptide-based nanomedicine with combined effects for enhanced tumor radio-immunotherapy
T Gao, Z Wang, J Zhou, D Wang, X Hou, X Lin… - Chemical Engineering …, 2024 - Elsevier
Despite the combination of radiotherapy and immunotherapy in clinical practice have shown
promising synergistic anti-tumor effect, the immunosuppressive tumor microenvironment …
promising synergistic anti-tumor effect, the immunosuppressive tumor microenvironment …
Dual-Enzyme-Instructed Peptide Self-Assembly to Boost Immunogenic Cell Death by Coordinating Intracellular Calcium Overload and Chemotherapy
Z Zhang, Y Hu, Y Ding, X Zhang, X Dong, L **e… - ACS …, 2025 - ACS Publications
The concept of immunogenic cell death (ICD) induced by chemotherapy as a potential
synergistic modality for cancer immunotherapy has been widely discussed. Unfortunately …
synergistic modality for cancer immunotherapy has been widely discussed. Unfortunately …
X-ray-activated nanoscintillators integrated with tumor-associated neutrophils polarization for improved radiotherapy in metastatic colorectal cancer
H Li, J Zeng, Q You, M Zhang, Y Shi, X Yang, W Gu… - Biomaterials, 2025 - Elsevier
Radiotherapy, employing high-energy rays to precisely target and eradicate tumor cells,
plays a pivotal role in the treatment of various malignancies. Despite its therapeutic …
plays a pivotal role in the treatment of various malignancies. Despite its therapeutic …
Hyaluronic acid-mediated targeted nano-modulators for activation of pyroptosis for cancer therapy through multichannel regulation of Ca2+ overload
L Li, Z **ng, J Wang, Y Guo, X Wu, Y Ma, Z Xu… - International Journal of …, 2025 - Elsevier
Calcium-based nanomaterials-mediated Ca 2+ overload-induced pyroptosis and its
application in tumor therapy have received considerable attention. However, the calcium …
application in tumor therapy have received considerable attention. However, the calcium …
Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects
Y Chen, S Shangguan, Z Lin, X Zeng, SY Chan… - …, 2024 - Wiley Online Library
X‐rays, a form of ionizing radiation with high energy and significant penetration capability,
are commonly used in clinical tumor treatment through radiotherapy. Despite their …
are commonly used in clinical tumor treatment through radiotherapy. Despite their …
Nanomaterial‐Mediated Modulation of TRPV1 Ion Channels for Biomedical Applications
Transient receptor potential vanilloid subtype 1 (TRPV1) is a nonselective cation channel
involved in various physiological processes such as pain perception, thermoregulation, and …
involved in various physiological processes such as pain perception, thermoregulation, and …