Albumin and mammalian cell culture: implications for biotechnology applications

GL Francis - Cytotechnology, 2010 - Springer
Albumin has a long historical involvement in design of media for the successful culture of
mammalian cells, in both the research and commercial fields. The potential application of …

Hypericin-the facts about a controversial agent

A Kubin, F Wierrani, U Burner, G Alth… - Current …, 2005 - benthamdirect.com
Hypericin is a naturally occurring substance found in the common St. Johns Wort
(Hypericum species) and can also be synthesized from the anthraquinone derivative …

Amyloid‐like protein aggregates: a new class of bioinspired materials merging an interfacial anchor with antifouling

X Hu, J Tian, C Li, H Su, R Qin, Y Wang… - Advanced …, 2020 - Wiley Online Library
Surfaces that resist nonspecific protein adsorption in a complex biological milieu are
required for a variety of applications. However, few strategies can achieve a robust …

Modification of polyethersulfone membrane by grafting bovine serum albumin on the surface of polyethersulfone/poly (acrylonitrile-co-acrylic acid) blended membrane

B Fang, Q Ling, W Zhao, Y Ma, P Bai, Q Wei… - Journal of Membrane …, 2009 - Elsevier
Polyethersulfone (PES) membrane was modified by blending with a copolymer of
acrylonitrile (AN) and acrylic acid (AA), followed by grafting bovine serum albumin (BSA) …

Hypericin photodynamic activity in DPPC liposomes–part II: stability and application in melanoma B16-F10 cancer cells

FAP de Morais, RS Gonçalves, BH Vilsinski… - Photochemical & …, 2020 - pubs.rsc.org
Hypericin (Hyp) is considered a promising photosensitizer for Photodynamic Therapy (PDT),
due to its high hydrophobicity, affinity for cell membranes, low toxicity and high …

Species differences in drug plasma protein binding

N Colclough, L Ruston, JM Wood, PA MacFaul - MedChemComm, 2014 - pubs.rsc.org
Comparison of the human plasma protein binding data for a variety of drug discovery
compounds indicates that compounds tend to be slightly more bound to human plasma …

Identification of the antitumoral drug emodin binding sites in bovine serum albumin by spectroscopic methods

P Sevilla, JM Rivas, F García-Blanco… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Using SERS, fluorescence, circular dichroism and stopped-flow, we have unequivocally
characterized the binding sites of emodin in bovine serum albumin. Emodin interacts with …

Serum albumins are efficient delivery systems for the photosensitizer hypericin in photosensitization-based treatments against Staphylococcus aureus

D Pezzuoli, M Cozzolino, C Montali, L Brancaleon… - Food Control, 2018 - Elsevier
The naturally occurring photosensitizer hypericin can be effectively delivered to bacterial
cells using serum albumins as biocompatible carriers. Using a combination of spectroscopic …

Hypericin–Apomyoglobin: An Enhanced Photosensitizer Complex for the Treatment of Tumor Cells

P Bianchini, M Cozzolino, M Oneto, L Pesce… - …, 2019 - ACS Publications
Bioavailability of photosensitizers for cancer photodynamic therapy is often hampered by
their low solubility in water. Here, we overcome this issue by using the water-soluble protein …

Necrosis avid near infrared fluorescent cyanines for imaging cell death and their use to monitor therapeutic efficacy in mouse tumor models

B **e, MA Stammes, PBAA van Driel, LJ Cruz… - …, 2015 - pmc.ncbi.nlm.nih.gov
Quantification of tumor necrosis in cancer patients is of diagnostic value as the amount of
necrosis is correlated with disease prognosis and it could also be used to predict early …