Neural contributions to muscle fatigue: from the brain to the muscle and back again

JL Taylor, M Amann, J Duchateau… - … and science in …, 2016 - pmc.ncbi.nlm.nih.gov
During exercise, there is a progressive reduction in the ability to produce muscle forces.
Processes within the nervous system, as well as within the muscles contribute to this fatigue …

Performance fatigability: mechanisms and task specificity

SK Hunter - Cold spring harbor perspectives in …, 2018 - perspectivesinmedicine.cshlp.org
Performance fatigability is characterized as an acute decline in motor performance caused
by an exercise-induced reduction in force or power of the involved muscles. Multiple …

[HTML][HTML] Mental fatigue induced by prolonged self-regulation does not exacerbate central fatigue during subsequent whole-body endurance exercise

B Pageaux, SM Marcora, V Rozand… - Frontiers in human …, 2015 - frontiersin.org
It has been shown that the mental fatigue induced by prolonged self-regulation increases
perception of effort and reduces performance during subsequent endurance exercise …

Prolonged mental exertion does not alter neuromuscular function of the knee extensors

B Pageaux, S Marcora… - Medicine and science …, 2013 - u-bourgogne.hal.science
Purpose: The aim of this study was to test the hypotheses that prolonged mental exertion i)
reduces maximal muscle activation and ii) increases the extent of central fatigue induced by …

Neural and computational mechanisms of momentary fatigue and persistence in effort-based choice

T Müller, MC Klein-Flügge, SG Manohar… - Nature …, 2021 - nature.com
From a gym workout, to deciding whether to persevere at work, many activities require us to
persist in deciding that rewards are 'worth the effort'even as we become fatigued. However …

Combined effects of fatigue and decision making on female lower limb landing postures: central and peripheral contributions to ACL injury risk

BS Borotikar, R Newcomer, R Koppes, SG McLean - Clinical biomechanics, 2008 - Elsevier
BACKGROUND: In spite of ongoing prevention developments, anterior cruciate ligament
injury rates and the associated sex-disparity have remained, suggesting an incomplete …

Supraspinal regulation of physical fatigue

M Tanaka, Y Watanabe - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
Fatigue, defined as difficulty in initiating or sustaining voluntary activities, can be classified
as physical or mental, and physical fatigue can be classified as peripheral or central (spinal …

Non-invasive NIR spectroscopy of human brain function during exercise

S Perrey - Methods, 2008 - Elsevier
The assessment of physiological changes associated with brain activity has become
possible by optical methods, such as near-infrared spectroscopy (NIRS). NIRS is a useful …

Disrupting the supplementary motor area makes physical effort appear less effortful

A Zénon, M Sidibé, E Olivier - Journal of Neuroscience, 2015 - jneurosci.org
The perception of physical effort is relatively unaffected by the suppression of sensory
afferences, indicating that this function relies mostly on the processing of the central motor …

Transcranial direct current stimulation (tDCS) for fatigue in multiple sclerosis

R Ferrucci, M Vergari, F Cogiamanian… - …, 2014 - content.iospress.com
Background: The debilitating fatigue that patients with multiple sclerosis (MS) commonly
experience during day-to-day living activities responds poorly to current therapeutic options …