High-throughput glycomic methods

I Trbojević-Akmačić… - Chemical …, 2022 - ACS Publications
Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

Aberrant PSA glycosylation—a sweet predictor of prostate cancer

S Gilgunn, PJ Conroy, R Saldova, PM Rudd… - Nature Reviews …, 2013 - nature.com
Prostate cancer—the most commonly diagnosed cancer in men worldwide—can have a
substantial effect on quality of life, regardless of the route the cancer takes. The serum PSA …

Application of lectin microarrays for biomarker discovery

K Dang, W Zhang, S Jiang, X Lin, A Qian - ChemistryOpen, 2020 - Wiley Online Library
Many proteins in living organisms are glycosylated. As their glycan patterns exhibit protein‐,
cell‐, and tissue‐specific heterogeneity, changes in the glycosylation levels could serve as …

Role of lectin microarrays in cancer diagnosis

P Syed, K Gidwani, H Kekki, J Leivo, K Pettersson… - …, 2016 - Wiley Online Library
The majority of cell differentiation associated tumor markers reported to date are either
glycoproteins or glycolipids. Despite there being a large number of glycoproteins reported …

Sweet systems: technologies for glycomic analysis and their integration into systems biology

S Chen, R Qin, LK Mahal - Critical reviews in biochemistry and …, 2021 - Taylor & Francis
Found in virtually every organism, glycans are essential molecules that play important roles
in almost every aspect of biology. The composition of glycome, the repertoire of glycans in …

Integrated tyramide and polymerization-assisted signal amplification for a highly-sensitive immunoassay

L Yuan, L Xu, S Liu - Analytical chemistry, 2012 - ACS Publications
A novel strategy for ultrasensitive detection of model protein based on the integration of
tyramide signal amplification (TSA) and polymerization-assisted signal amplification was …

[КНИГА][B] Electrochemical analysis of proteins and cells

G Li, P Miao - 2012 - books.google.com
Electrochemical Analysis of Proteins and Cells presents the remarkable progress made over
the years in the electrochemical analysis of proteins and cells, due to the rapid development …

Horseradish peroxidase-repeat assay based on tyramine signal amplification for highly sensitive H 2 O 2 detection by surface-enhanced Raman scattering

C Fu, Y Wang, X Tian, Y Wu, H Cao, Y Li, YM Jung - Analyst, 2021 - pubs.rsc.org
A new and simple surface-enhanced Raman scattering (SERS) biosensor based on the
tyramine signal amplification (TSA)-triggered formation of horseradish peroxidase (HRP) …

Lectin Microarray-Based Sero-Biomarker Verification Targeting Aberrant O-Linked Glycosylation on Mucin 1

A Matsuda, A Kuno, T Nakagawa, Y Ikehara… - Analytical …, 2015 - ACS Publications
Glycoform of mucin 1 (MUC1) in cancerous cells changes markedly with cell differentiation,
and thus, qualitative detection and verification of the MUC1 glycosylation changes have …

Improved cancer specificity in PSA assay using Aleuria aurantia lectin coated Eu-nanoparticles for detection

H Kekki, M Peltola, S van Vliet, C Bangma… - Clinical …, 2017 - Elsevier
Objectives The objective was to study the differences in PSA fucosylation obtained from
LNCaP and PC-3 prostate cancer cell lines, seminal plasma PSA and recombinant …