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Extracellular vesicles as tools and targets in therapy for diseases
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
The role of platelets in immune-mediated inflammatory diseases
Immune-mediated inflammatory diseases (IMIDs) are characterized by excessive and
uncontrolled inflammation and thrombosis, both of which are responsible for organ damage …
uncontrolled inflammation and thrombosis, both of which are responsible for organ damage …
A compendium of single extracellular vesicle flow cytometry
JA Welsh, GJA Arkesteijn, M Bremer… - Journal of …, 2023 - Wiley Online Library
Flow cytometry (FCM) offers a multiparametric technology capable of characterizing single
extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells …
extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells …
Understanding the extracellular vesicle surface for clinical molecular biology
Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …
Circulating platelets as mediators of immunity, inflammation, and thrombosis
M Koupenova, L Clancy, HA Corkrey… - Circulation …, 2018 - ahajournals.org
Platelets, non-nucleated blood components first described over 130 years ago, are
recognized as the primary cell regulating hemostasis and thrombosis. The vascular …
recognized as the primary cell regulating hemostasis and thrombosis. The vascular …
Modification of extracellular vesicles by fusion with liposomes for the design of personalized biogenic drug delivery systems
Extracellular vesicles (EVs) are recognized as nature's own carriers to transport
macromolecules throughout the body. Hijacking this endogenous communication system …
macromolecules throughout the body. Hijacking this endogenous communication system …
Platelet extracellular vesicles: beyond the blood
Extracellular vesicles (EVs) are a means of cell-to-cell communication and can facilitate the
exchange of a broad array of molecules between adjacent or distant cells. Platelets are …
exchange of a broad array of molecules between adjacent or distant cells. Platelets are …
Mesenchymal stem cell-derived exosomes: a new therapeutic approach to osteoarthritis?
Degenerative disorders of joints, especially osteoarthritis (OA), result in persistent pain and
disability and high costs to society. Nevertheless, the molecular mechanisms of OA have not …
disability and high costs to society. Nevertheless, the molecular mechanisms of OA have not …
Molecular interactions at the surface of extracellular vesicles
Extracellular vesicles such as exosomes, microvesicles, apoptotic bodies, and large
oncosomes have been shown to participate in a wide variety of biological processes and are …
oncosomes have been shown to participate in a wide variety of biological processes and are …
Ticket to a bubble ride: Cargo sorting into exosomes and extracellular vesicles
Extracellular vesicles (EVs) are released by cells into the extracellular milieu to facilitate
intercellular communication in both physiological and pathological condition. EVs contain …
intercellular communication in both physiological and pathological condition. EVs contain …