A practical guide to amplicon and metagenomic analysis of microbiome data

YX Liu, Y Qin, T Chen, M Lu, X Qian, X Guo… - Protein & cell, 2021 - academic.oup.com
Advances in high-throughput sequencing (HTS) have fostered rapid developments in the
field of microbiome research, and massive microbiome datasets are now being generated …

Best practices in metabarcoding of fungi: from experimental design to results

L Tedersoo, M Bahram, L Zinger, RH Nilsson… - Molecular …, 2022 - Wiley Online Library
The development of high‐throughput sequencing (HTS) technologies has greatly improved
our capacity to identify fungi and unveil their ecological roles across a variety of ecosystems …

Introducing the bacterial and viral bioinformatics resource center (BV-BRC): a resource combining PATRIC, IRD and ViPR

RD Olson, R Assaf, T Brettin, N Conrad… - Nucleic acids …, 2023 - academic.oup.com
Abstract The National Institute of Allergy and Infectious Diseases (NIAID) established the
Bioinformatics Resource Center (BRC) program to assist researchers with analyzing the …

Spillover of highly pathogenic avian influenza H5N1 virus to dairy cattle

LC Caserta, EA Frye, SL Butt, M Laverack… - Nature, 2024 - nature.com
The highly pathogenic avian influenza (HPAI) H5N1 virus clade 2.3. 4.4 b has caused the
death of millions of domestic birds and thousands of wild birds in the USA since January …

Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4

A Blanco-Míguez, F Beghini, F Cumbo, LJ McIver… - Nature …, 2023 - nature.com
Metagenomic assembly enables new organism discovery from microbial communities, but it
can only capture few abundant organisms from most metagenomes. Here we present …

Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation

S Federici, S Kredo-Russo, R Valdés-Mas… - Cell, 2022 - cell.com
Human gut commensals are increasingly suggested to impact non-communicable diseases,
such as inflammatory bowel diseases (IBD), yet their targeted suppression remains a …

Nivolumab plus ipilimumab with or without live bacterial supplementation in metastatic renal cell carcinoma: a randomized phase 1 trial

N Dizman, L Meza, P Bergerot, M Alcantara, T Dorff… - Nature medicine, 2022 - nature.com
Previous studies have suggested that the gut microbiome influences the response to
checkpoint inhibitors (CPIs) in patients with cancer. CBM588 is a bifidogenic live bacterial …

Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance

P Munk, C Brinch, FD Møller, TN Petersen… - Nature …, 2022 - nature.com
Antimicrobial resistance (AMR) is a major threat to global health. Understanding the
emergence, evolution, and transmission of individual antibiotic resistance genes (ARGs) is …

The IMG/M data management and analysis system v. 7: content updates and new features

IMA Chen, K Chu, K Palaniappan, A Ratner… - Nucleic acids …, 2023 - academic.oup.com
Abstract The Integrated Microbial Genomes & Microbiomes system (IMG/M: https://img. jgi.
doe. gov/m/) at the Department of Energy (DOE) Joint Genome Institute (JGI) continues to …

Intestinal microbiota signatures of clinical response and immune-related adverse events in melanoma patients treated with anti-PD-1

JA McCulloch, D Davar, RR Rodrigues, JH Badger… - Nature medicine, 2022 - nature.com
Ample evidence indicates that the gut microbiome is a tumor-extrinsic factor associated with
antitumor response to anti-programmed cell death protein-1 (PD-1) therapy, but …