Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics

L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …

Social participation and risk of develo** dementia

A Sommerlad, M Kivimäki, EB Larson, S Röhr, K Shirai… - Nature aging, 2023 - nature.com
The increasing number of people with dementia globally illustrates the urgent need to
reduce dementia's scale and impact. Lifetime social participation may affect dementia risk by …

Fruits, vegetables, and health: A comprehensive narrative, umbrella review of the science and recommendations for enhanced public policy to improve intake

TC Wallace, RL Bailey, JB Blumberg… - Critical reviews in …, 2020 - Taylor & Francis
Fruit and vegetables (F&V) have been a cornerstone of healthy dietary recommendations;
the 2015–2020 US Dietary Guidelines for Americans recommend that F&V constitute one …

The ageing brain: molecular and cellular basis of neurodegeneration

S Azam, ME Haque, R Balakrishnan, IS Kim… - Frontiers in cell and …, 2021 - frontiersin.org
Ageing is an inevitable event in the lifecycle of all organisms, characterized by progressive
physiological deterioration and increased vulnerability to death. Ageing has also been …

2018 Alzheimer's disease facts and figures

Alzheimer's Association - Alzheimer's & Dementia, 2018 - Elsevier
This article describes the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality and morbidity, costs of care, and the overall impact on …

Nutrition and prevention of cognitive impairment

N Scarmeas, CA Anastasiou… - The Lancet Neurology, 2018 - thelancet.com
Nutrition is an important lifestyle factor that can modify the risk of future cognitive impairment
and dementia. Some, but not conclusive, evidence (mostly from observational studies and …

2016 Alzheimer's disease facts and figures

Alzheimer's Association - Alzheimer's & Dementia, 2016 - Elsevier
This report describes the public health impact of Alzheimer's disease, including incidence
and prevalence, mortality rates, costs of care, and the overall impact on caregivers and …

Low-grade inflammation, diet composition and health: current research evidence and its translation

AM Minihane, S Vinoy, WR Russell, A Baka… - British Journal of …, 2015 - cambridge.org
The importance of chronic low-grade inflammation in the pathology of numerous age-related
chronic conditions is now clear. An unresolved inflammatory response is likely to be …

2015 Alzheimer's disease facts and figures

Alzheimer's Association - Alzheimer's & Dementia, 2015 - Wiley Online Library
This report discusses the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality rates, costs of care and the overall effect on caregivers …

2017 Alzheimer's disease facts and figures

Alzheimer's Association - Alzheimer's & Dementia, 2017 - Elsevier
This article describes the public health impact of Alzheimer's disease (AD), including
incidence and prevalence, mortality rates, costs of care, and the overall impact on caregivers …