The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Semiconductor quantum dots (QDs) have become important fluorescent probes for in vitro
and in vivo bioimaging research. Their nanoparticle surfaces for versatile bioconjugation …

2. INTRODUCTION The investigation of many fundamental processes in life sciences
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …

The use of semiconductor quantum dots (QDs) in biological sensing and labeling continues
to grow with each year. Current and projected applications include use as fluorescent labels …

Cationic lipid-and polymer-based nanodevices are considered appropriate alternatives for
virus-based particles for delivery of nucleic acids, including genes and siRNA, into …

Cancer is a broad term for a class of prevalent diseases as one in three people develop
cancer during their lifetime. Although, there are few success stories of cancer therapy, most …

Lipoplexes and polyplexes, electrostatic complexes between a plasmid DNA and cationic
lipids or polymers are chemical systems that are developed for gene delivery. Considerable …

Significant effort continues to be exerted toward the improvement of transfection mediated by
nonviral vectors. These endeavors are often focused on the design of particulate carriers …

Polymer-based nanomedicine is a large and fast growing field. Polymer-based systems
have been extensively used as therapeutic carriers as well as bioimaging agents for …

Polyplex-mediated gene transfection is now in its' fourth decade of serious research, but the
promise of polyplex-mediated gene therapy has yet to fully materialize. Only approximately …