Pyrazole is a five-membered aromatic heterocyclic ring with two adjacent nitrogen atoms C 3
H 3 N 2 H. The presence of this nucleus in pharmacological agents of various therapeutic …

Various imidazole-containing compounds have been tested for their medical usefulness in
clinical trials for several disease conditions. The rapid expansion of imidazole-based …

Cancer is a black spot on the face of humanity in this era of science and technology.
Presently, several classes of anticancer drugs are available in the market, but issues such …

Highlights•Molecular medicinal properties: Pharmacodynamics, physiochemical and
pharmacokinetic properties (P3-properties).•Successful innovation: Drug to drug, Drug to …

Focusing on the literature progress since 2002, the present review explores the highly
significant role that multicomponent reactions (MCRs) have played as a very important tool …

1. INTRODUCTION The length of straightened-out DNA in a single cell is nearly 2 m. In
mammalian cells, the nucleus has a diameter of approximately 6 μm and occupies about …

Imidazo [1, 2‐a] pyridine is a well‐known scaffold in many marketed drugs, such as
Zolpidem, Minodronic acid, Miroprofen and DS‐1 and it also serves as a broadly applied …

Abstract The Groebke–Blackburn–Bienaymé reaction (GBBR) is used for the one-pot
synthesis of therapeutically relevant fused imidazoles bridgehead nitrogen heterocyclic …

Multicomponent reactions (MCRs) are extremely popular owing to their facile execution,
high atom-efficiency and the high diversity of products. MCRs can be used to access various …

In this paper, we developed a reusable heterogeneous non-precious iron nanocomposite
comprising metallic Fe–Fe3C nanoparticles and Fe–Nx sites on N-doped porous carbon …