Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which
is of great significance to tissue development. ECM in muscle fiber niche consists of three …

Cytokines are important mediators of various aspects of health and disease, including
appetite, glucose and lipid metabolism, insulin sensitivity, skeletal muscle hypertrophy and …

Quantitative proteomics has traditionally been performed by two-dimensional gel
electrophoresis, but recently, mass spectrometric methods based on stable isotope …

Abstract Kjær, Michael. Role of Extracellular Matrix in Adaptation of Tendon and Skeletal
Muscle to Mechanical Loading. Physiol Rev 84: 649–698, 2004; 10.1152/physrev …

It is generally accepted that the primary mechanisms governing skeletal muscle hypertrophy
are satellite cell activation, proliferation, and differentiation. Specific growth factors and …

Declining stem cell function during aging contributes to impaired tissue function. Muscle‐
specific stem cells ('satellite cells') are responsible for generating new muscle in response to …

The assembly of sarcomeres, the smallest contractile units in striated muscle, is a complex
and highly coordinated process that relies on spatio-temporal organization of sarcomeric …

UPF1 functions in both Staufen 1 (STAU1)-mediated mRNA decay (SMD) and nonsense-
mediated mRNA decay (NMD), which we show here are competitive pathways. STAU1-and …

In Duchenne muscular dystrophy (DMD) and the mdx mouse model, the absence of the
cytoskeletal protein dystrophin causes defective anchoring of myofibres to the basal lamina …

Duchenne muscular dystrophy (DMD) is the most common inherited neuromuscular
disease, and is characterized by the lack of dystrophin, muscle wasting, increased …