Pharmaceutical particle technology is employed to improve poor aqueous solubility of drug
compounds that limits in vivo bioavailability owing to their low dissolution rate in the …

Milling involves the application of mechanical energy to physically break down coarse
particles to finer ones and is regarded as a “top–down” approach in the production of fine …

Conventional immediate release dosage forms involve compressing the powder with a
disintegrating agent that enables rapid disintegration and dissolution upon oral ingestion …

ABSTRACT Introduction: Dry powder inhalers (DPIs) are popular for pulmonary drug
delivery. Various techniques have been employed to produce inhalation drug particles and …

Improvement in flow and bulk density, the two most important properties that determine the
ease with which pharmaceutical powders can be handled, stored and processed, is done …

The flowability of powders used in tableting significantly affects tablet weight and content
uniformity of active pharmaceutical ingredients. Use of granulated materials instead of …

The aim of this paper was to explore tablet design options for FDM 3D printing for
simultaneous tailoring of drug release and dose. The drug, griseofulvin (GF), the polymer …

Understanding interparticle interactions in powder systems is crucial to pharmaceutical
powder processing. Nevertheless, there remains a great challenge in identifying the key …

This research determined the proportions of lidocaine conformer groups in a supercritical
carbon dioxide environment at constant pressures (10, 20 and 30 MPa) and temperatures of …

Grinding aid additives are established in various industrial dry fine grinding processes,
primarily to achieve either a) an increase of the production capacity, b) a decrease of the …