The crucial role and mechanism of insulin resistance in metabolic disease

X Zhao, X An, C Yang, W Sun, H Ji… - Frontiers in endocrinology, 2023‏ - frontiersin.org
Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …

[HTML][HTML] Magnesium in prevention and therapy

U Gröber, J Schmidt, K Kisters - Nutrients, 2015‏ - mdpi.com
Magnesium is the fourth most abundant mineral in the body. It has been recognized as a
cofactor for more than 300 enzymatic reactions, where it is crucial for adenosine …

The role of magnesium in the pathogenesis of metabolic disorders

M Pelczyńska, M Moszak, P Bogdański - Nutrients, 2022‏ - mdpi.com
Magnesium (Mg) is an essential nutrient for maintaining vital physiological functions. It is
involved in many fundamental processes, and Mg deficiency is often correlated with …

Effects of magnesium deficiency on mechanisms of insulin resistance in type 2 diabetes: focusing on the processes of insulin secretion and signaling

K Kostov - International journal of molecular sciences, 2019‏ - mdpi.com
Magnesium (Mg2+) is an essential mineral for human health and plays an important role in
the regulation of glucose homeostasis and insulin actions. Despite the widespread clinical …

The importance of magnesium in clinical healthcare

GK Schwalfenberg, SJ Genuis - Scientifica, 2017‏ - Wiley Online Library
The scientific literature provides extensive evidence of widespread magnesium deficiency
and the potential need for magnesium repletion in diverse medical conditions. Magnesium is …

Magnesium deficiency and increased inflammation: current perspectives

FH Nielsen - Journal of inflammation research, 2018‏ - Taylor & Francis
Animal studies have shown that magnesium deficiency induces an inflammatory response
that results in leukocyte and macrophage activation, release of inflammatory cytokines and …

Magnesium and type 2 diabetes

M Barbagallo, LJ Dominguez - World journal of diabetes, 2015‏ - pmc.ncbi.nlm.nih.gov
Type 2 diabetes is frequently associated with both extracellular and intracellular magnesium
(Mg) deficits. A chronic latent Mg deficit or an overt clinical hypomagnesemia is common in …

Dietary magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality: a dose–response meta-analysis of prospective cohort …

X Fang, K Wang, D Han, X He, J Wei, L Zhao, MU Imam… - BMC medicine, 2016‏ - Springer
Background Although studies have examined the association between dietary magnesium
intake and health outcome, the results are inconclusive. Here, we conducted a dose …

Role of magnesium deficiency in promoting atherosclerosis, endothelial dysfunction, and arterial stiffening as risk factors for hypertension

K Kostov, L Halacheva - International journal of molecular sciences, 2018‏ - mdpi.com
Arterial hypertension is a disease with a complex pathogenesis. Despite considerable
knowledge about this socially significant disease, the role of magnesium deficiency (MgD) …

Suboptimal magnesium status in the United States: are the health consequences underestimated?

A Rosanoff, CM Weaver, RK Rude - Nutrition reviews, 2012‏ - academic.oup.com
In comparison with calcium, magnesium is an “orphan nutrient” that has been studied
considerably less heavily. Low magnesium intakes and blood levels have been associated …