With approximately 7000 species, snakes and lizards, collectively known as squamates, are
by far the most species‐rich group of reptiles. It was from reptile‐like ancestors that …

The sarcoplasmic reticulum (SR) is crucial for contraction and relaxation of the mammalian
cardiomyocyte, but its role in other vertebrate classes is equivocal. Recent evidence …

In the 1950s, Arthur C. Guyton removed the heart from its pedestal in cardiovascular
physiology by arguing that cardiac output is primarily regulated by the peripheral …

The electrocardiogram (ECG) reveals that heart chamber activation and repolarization are
much faster in mammals and birds compared to ectothermic vertebrates of similar size …

Constricting pythons, known for their ability to consume infrequent, massive meals, exhibit
rapid and reversible cardiac hypertrophy following feeding. Our primary goal was to …

Oxygen deprivation during embryonic development can permanently remodel the vertebrate
heart, often causing cardiovascular abnormalities in adulthood. While this phenomenon is …

Phospholamban (PLN) is a small phosphoprotein closely associated with the cardiac
sarcoplasmic reticulum (SR). Dephosphorylated PLN tonically inhibits the SR C a‐ATP ase …

We measured the temperature sensitivity, adrenergic sensitivity, and dependence on
sarcoplasmic reticulum (SR) Ca2+ of ventricular muscle from pelagic fishes with different …

Certain vertebrates, such as freshwater turtles of the genus Chrysemys and Trachemys and
crucian carp (Carassius carassius), have anoxia-tolerant hearts that continue to function …

Cardiac activity of the turtle (Trachemys scripta) is greatly depressed with cold acclimation
and anoxia. We examined what electrophysiological modifications accompany and perhaps …