High-throughput DNA de novo synthesis has drawn extensive attention from academia and
bioindustry due to its fundamental importance in applications such as gene synthesis, drug …

New synthetic biology capabilities hold the promise of dramatically improving our ability to
engineer biological systems. However, a fundamental hurdle in realizing this potential is our …

Genetic manipulation is one of the central strategies that biologists use to investigate the
molecular underpinnings of life and its diversity. Thus, advances in genetic manipulation …

Over recent years, studies on microbiota research and synthetic biology have explored
novel approaches microbial manipulation for therapeutic purposes. However, fragmented …

Advances in reading, writing and editing genetic materials have greatly expanded our ability
to reprogram biological systems at the resolution of a single nucleotide and on the scale of a …

DNA self-assembly offers a powerful means to construct complex nanostructures and
program dynamic molecular processes such as strand displacement. DNA nanosystems …

Based on the BioBricks™ standard, restriction synthesis is a novel catabolic iterative DNA
synthesis method that utilizes endonucleases to synthesize a query sequence from a …

The application of array-based oligonucleotides in biological studies is described. These
oligonucleotides are mainly used to design large libraries of various nucleotide sequences …

Aptamers feature a number of advantages, compared to antibodies. However, their
application has been limited so far, mainly because of the complex selection process.'High …

Deoxyribonucleic acid or DNA is an essential component in cells and organisms for genetic
information storage and transduction. The base paring chemistry offers excellent …