Exercise metabolism and adaptation in skeletal muscle

JAB Smith, KA Murach, KA Dyar… - Nature Reviews Molecular …, 2023 - nature.com
Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …

Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

[HTML][HTML] Circadian clock interaction with HIF1α mediates oxygenic metabolism and anaerobic glycolysis in skeletal muscle

CB Peek, DC Levine, J Cedernaes, A Taguchi… - Cell metabolism, 2017 - cell.com
Circadian clocks are encoded by a transcription-translation feedback loop that aligns
energetic processes with the solar cycle. We show that genetic disruption of the clock …

Circadian system and glucose metabolism: implications for physiology and disease

J Qian, FAJL Scheer - Trends in Endocrinology & Metabolism, 2016 - cell.com
The circadian system serves one of the most fundamental properties present in nearly all
organisms: it generates 24-h rhythms in behavioral and physiological processes and …

Circadian clocks in the digestive system

A Segers, I Depoortere - Nature Reviews Gastroenterology & …, 2021 - nature.com
Many molecular, physiological and behavioural processes display distinct 24-hour rhythms
that are directed by the circadian system. The master clock, located in the suprachiasmatic …

Circadian etiology of type 2 diabetes mellitus

N Javeed, AV Matveyenko - Physiology, 2018 - journals.physiology.org
The epidemic of Type 2 diabetes mellitus necessitates development of novel therapeutic
and preventative strategies to attenuate expansion of this debilitating disease. Evidence …

Circadian rhythms in mitochondrial respiration

P De Goede, J Wefers, EC Brombacher… - Journal of …, 2018 - jme.bioscientifica.com
Many physiological processes are regulated with a 24-h periodicity to anticipate the
environmental changes of daytime to nighttime and vice versa. These 24-h regulations …

Muscle‐bone crosstalk and potential therapies for sarco‐osteoporosis

GB Li, L Zhang, DE Wang, L AIQudsy… - Journal of cellular …, 2019 - Wiley Online Library
The nature of muscle‐bone crosstalk has been historically considered to be only
mechanical, where the muscle is the load applier while bone provides the attachment sites …

Chrono-nutrition: a review of current evidence from observational studies on global trends in time-of-day of energy intake and its association with obesity

S Almoosawi, S Vingeliene, LG Karagounis… - Proceedings of the …, 2016 - cambridge.org
The importance of the circadian rhythm in regulating human food intake behaviour and
metabolism has long been recognised. However, little is known as to how energy intake is …

Coupled network of the circadian clocks: a driving force of rhythmic physiology

AM Finger, C Dibner, A Kramer - FEBS letters, 2020 - Wiley Online Library
The circadian system is composed of coupled endogenous oscillators that allow living
beings, including humans, to anticipate and adapt to daily changes in their environment. In …