Architecture of the subthalamic nucleus

AA Prasad, Å Wallén-Mackenzie - Communications Biology, 2024 - nature.com
The subthalamic nucleus (STN) is a major neuromodulation target for the alleviation of
neurological and neuropsychiatric symptoms using deep brain stimulation (DBS). STN-DBS …

Concerning neuromodulation as treatment of neurological and neuropsychiatric disorder: insights gained from selective targeting of the subthalamic nucleus, para …

A Ricci, E Rubino, GP Serra, Å Wallén-Mackenzie - Neuropharmacology, 2024 - Elsevier
Neuromodulation such as deep brain stimulation (DBS) is advancing as a clinical
intervention in several neurological and neuropsychiatric disorders, including Parkinson´ s …

Cross-frequency coupling between gamma oscillations and deep brain stimulation frequency in Parkinson's disease

M Muthuraman, M Bange, N Koirala, D Ciolac, B Pintea… - Brain, 2020 - academic.oup.com
The disruption of pathologically enhanced beta oscillations is considered one of the key
mechanisms mediating the clinical effects of deep brain stimulation on motor symptoms in …

Efficacy of subthalamic deep brain stimulation programming strategies for gait disorders in Parkinson's disease: a systematic review and meta-analysis

NCB Tortato, G Ribas, LA Frizon, M Farah… - Neurosurgical …, 2024 - Springer
Patients with advanced Parkinson's disease often suffer from severe gait and balance
problems, impacting quality of live and persisting despite optimization of standard therapies …

Directional subthalamic deep brain stimulation better improves gait and balance disorders in Parkinson's disease patients: a randomized controlled study

S Cherif, N Tempier, M Yeche, G Temiz… - Annals of …, 2025 - Wiley Online Library
Objective To investigate the effects of directional subthalamic deep brain stimulation (STN‐
dDBS) on gait and balance disorders, including freezing of gait (FOG), in patients with …

Subthalamic 85 Hz deep brain stimulation improves walking pace and stride length in Parkinson's disease patients

F Mügge, U Kleinholdermann, A Heun… - … Research and Practice, 2023 - Springer
Background Mobile gait sensors represent a compelling tool to objectify the severity of
symptoms in patients with idiopathic Parkinson's disease (iPD), but also to determine the …

Three-year gait and axial outcomes of bilateral STN and GPi Parkinson's disease deep brain stimulation

S Mei, RS Eisinger, W Hu, T Tsuboi… - Frontiers in human …, 2020 - frontiersin.org
Objective: To examine the short-and long-term clinical outcomes of the bilateral subthalamic
nucleus (STN) and globus pallidus internus (GPi) deep brain stimulation (DBS) on gait and …

Subthalamic nucleus deep brain stimulation for Parkinson's disease: current trends and future directions

A Macerollo, L Zrinzo, H Akram, T Foltynie… - Expert review of …, 2020 - Taylor & Francis
Over the last three decades, extensive basic and clinical research has been performed on
the use of subthalamic nucleus (STN) as the preferred deep brain stimulation (DBS) target …

Entraining step** movements of Parkinson's patients to alternating subthalamic nucleus deep brain stimulation

P Fischer, S He, A de Roquemaurel, H Akram… - Journal of …, 2020 - jneurosci.org
Patients with advanced Parkinson's can be treated by deep brain stimulation (DBS) of the
subthalamic nucleus (STN). This affords a unique opportunity to record from this nucleus …

Parkinson's disease symptoms associated with develo** on-state axial symptoms early after subthalamic deep brain stimulation

G Fernández-Pajarín, Á Sesar, JL Relova, B Ares… - Diagnostics, 2022 - mdpi.com
Background: The relationship between axial symptoms in Parkinson's disease (PD) and
subthalamic deep brain stimulation (STN-DBS) is still unclear. Purpose: We searched for …