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NGF and BDNF in pediatrics syndromes
G Ferraguti, S Terracina, G Micangeli… - Neuroscience & …, 2023 - Elsevier
Neurotrophins (NTs) as nerve growth factor (NGF) and brain-derived neurotrophic factor
(BDNF) play multiple roles in different settings including neuronal development, function and …
(BDNF) play multiple roles in different settings including neuronal development, function and …
Abnormal mTOR activation in autism
The mechanistic target of rapamycin (mTOR) is an important signaling hub that integrates
environmental information regarding energy availability and stimulates anabolic molecular …
environmental information regarding energy availability and stimulates anabolic molecular …
Brain-derived neurotrophic factor levels in autism: a systematic review and meta-analysis
Brain-derived neurotrophic factor (BDNF) plays an important role in activity-dependent
synaptic plasticity. Altered blood BDNF levels have been frequently identified in people with …
synaptic plasticity. Altered blood BDNF levels have been frequently identified in people with …
Self-injurious behavior
S Huisman, P Mulder, J Kuijk, M Kerstholt… - Neuroscience & …, 2018 - Elsevier
Self-injurious behavior (SIB) is a relatively common behavior in individuals with intellectual
disabilities (ID). Severe SIB can be devastating and potentially life-threatening. There is …
disabilities (ID). Severe SIB can be devastating and potentially life-threatening. There is …
Unmet clinical needs and burden in Angelman syndrome: a review of the literature
Background Angelman syndrome (AS) is a rare disorder with a relatively well-defined
phenotype. Despite this, very little is known regarding the unmet clinical needs and burden …
phenotype. Despite this, very little is known regarding the unmet clinical needs and burden …
Measuring what matters to individuals with Angelman syndrome and their families: development of a patient-centered disease concept model
Angelman syndrome (AS) is a complex, heterogeneous, and life-long neurodevelopmental
disorder. Despite the considerable impact on individuals and caregivers, no disease …
disorder. Despite the considerable impact on individuals and caregivers, no disease …
Assessment of BDNF serum levels as a diagnostic marker in children with autism spectrum disorder
AG Barbosa, R Pratesi, GSC Paz, MAAL Dos Santos… - Scientific Reports, 2020 - nature.com
There has been a significant increase in autism spectrum disorder (ASD) in the last decades
that cannot be exclusively attributed to better diagnosis and an increase in the …
that cannot be exclusively attributed to better diagnosis and an increase in the …
Developmental skills of individuals with Angelman syndrome assessed using the Bayley-III
We describe the development of 236 children with Angelman syndrome (AS) using the
Bayley Scales of Infant and Toddler Development, Third Edition. Multilevel linear mixed …
Bayley Scales of Infant and Toddler Development, Third Edition. Multilevel linear mixed …
Long noncoding RNA and its contribution to autism spectrum disorders
Recent studies have indicated that long noncoding RNAs (lncRNAs) play important roles in
multiple processes, such as epigenetic regulation, gene expression regulation …
multiple processes, such as epigenetic regulation, gene expression regulation …
Meta-analysis of BDNF levels in autism
Brain-derived neurotrophic factor (BDNF) centrally mediates growth, differentiation and
survival of neurons, and the synaptic plasticity that underlies learning and memory. Recent …
survival of neurons, and the synaptic plasticity that underlies learning and memory. Recent …