Emerging role of exosomes in cancer progression and tumor microenvironment remodeling
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …
Recent advances in exosome-mediated nucleic acid delivery for cancer therapy
Y Zhang, Q Liu, X Zhang, H Huang, S Tang… - Journal of …, 2022 - Springer
Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …
challenge, although significant progress has been made in existing treatments in recent …
Aptamer-based targeted delivery of functional nucleic acids
S **e, W Sun, T Fu, X Liu, P Chen, L Qiu… - Journal of the …, 2023 - ACS Publications
Functional nucleic acid (NA)-based drugs have a broad range of applications since they
allow the alteration and control of gene/protein expression patterns in cells. In principle …
allow the alteration and control of gene/protein expression patterns in cells. In principle …
Extracellular vesicles in cancer drug resistance: roles, mechanisms, and implications
Q Yang, J Xu, J Gu, H Shi, J Zhang, J Zhang… - Advanced …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are cell‐derived nanosized vesicles that mediate cell‐to‐cell
communication via transporting bioactive molecules and thus are critically involved in …
communication via transporting bioactive molecules and thus are critically involved in …
Exosomes: a review of biologic function, diagnostic and targeted therapy applications, and clinical trials
Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids,
proteins, lipids, and metabolites. They mediate the exchange of substances between cells …
proteins, lipids, and metabolites. They mediate the exchange of substances between cells …
Tumor-derived small extracellular vesicles in cancer invasion and metastasis: Molecular mechanisms, and clinical significance
C Zhang, C Qin, S Dewanjee, H Bhattacharya… - Molecular Cancer, 2024 - Springer
The production and release of tumor-derived small extracellular vesicles (TDSEVs) from
cancerous cells play a pivotal role in the propagation of cancer, through genetic and …
cancerous cells play a pivotal role in the propagation of cancer, through genetic and …
Tumor-targeted exosomes for delivery of anticancer drugs
Exosomes are small phospholipid bilayer vesicles that are naturally produced by all living
cells, both prokaryotes and eukaryotes. The exosomes due to their unique size, reduced …
cells, both prokaryotes and eukaryotes. The exosomes due to their unique size, reduced …
Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …
Microfluidics for detection of exosomes and microRNAs in cancer: State of the art
Exosomes are small extracellular vesicles with sizes ranging from 30–150 nanometers that
contain proteins, lipids, mRNAs, microRNAs, and double-stranded DNA derived from the …
contain proteins, lipids, mRNAs, microRNAs, and double-stranded DNA derived from the …
Exosome-based nanomedicine for cancer treatment by targeting inflammatory pathways: current status and future perspectives
Cancer is one of the dreadful diseases worldwide. Surgery, radiation and chemotherapy, are
the three basic standard modes of cancer treatment. However, difficulties in cancer treatment …
the three basic standard modes of cancer treatment. However, difficulties in cancer treatment …