Fast-track development of vaccines for SARS-CoV-2: the shots that saved the world
In December 2019, an outbreak emerged of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) which leads to coronavirus disease 2019 (COVID-19). The World Health …
2 (SARS-CoV-2) which leads to coronavirus disease 2019 (COVID-19). The World Health …
COVID-19 and vaccination: myths vs science
Introduction Several vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been developed since the inception of the coronavirus disease 2019 …
(SARS-CoV-2) have been developed since the inception of the coronavirus disease 2019 …
Toll-like receptor signaling in severe acute respiratory syndrome coronavirus 2-induced innate immune responses and the potential application value of toll-like …
J Dai, Y Wang, H Wang, Z Gao, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Toll-like receptors (TLRs) are key sensors that recognize the pathogen-associated
molecular patterns (PAMPs) of severe acute respiratory syndrome coronavirus 2 (SARS …
molecular patterns (PAMPs) of severe acute respiratory syndrome coronavirus 2 (SARS …
Molecular modelling and structure-activity relationship of a natural derivative of o-hydroxybenzoate as a potent inhibitor of dual NSP3 and NSP12 of SARS-CoV-2: In …
The nsp3 macrodomain and nsp12 (RdRp) enzymes are strongly implicated in the virulent
regulation of the host immune response and viral replication of SARS-CoV-2, making them …
regulation of the host immune response and viral replication of SARS-CoV-2, making them …
Extracellular vesicle associated miRNAs regulate signaling pathways involved in COVID-19 pneumonia and the progression to severe acute respiratory corona virus …
Background Extracellular vesicles (EVs) are mediators of cell-to-cell communication in
inflammatory lung diseases. They function as carriers for miRNAs which regulate mRNA …
inflammatory lung diseases. They function as carriers for miRNAs which regulate mRNA …
Role of angiotensin II in cardiovascular diseases: Introducing bisartans as a novel therapy for coronavirus 2019
Cardiovascular diseases (CVDs) are the main contributors to global morbidity and mortality.
Major pathogenic phenotypes of CVDs include the development of endothelial dysfunction …
Major pathogenic phenotypes of CVDs include the development of endothelial dysfunction …
Protein subunit vaccines: Promising frontiers against COVID-19
The emergence of COVID-19 has posed an unprecedented global health crisis, challenging
the healthcare systems worldwide. Amidst the rapid development of several vaccine …
the healthcare systems worldwide. Amidst the rapid development of several vaccine …
Dendritic cell-based vaccine: The state-of-the-art vaccine platform for COVID-19 management
Introduction A correlation between new coronaviruses and host immunity, as well as the role
of defective immune function in host response, would be extremely helpful in understanding …
of defective immune function in host response, would be extremely helpful in understanding …
Novel benzimidazole angiotensin receptor blockers with anti-SARS-CoV-2 activity equipotent to that of nirmatrelvir: computational and enzymatic studies
Background Hypertension worsens outcomes in SARS-CoV-2 patients. Sartans, a type of
antihypertensive angiotensin receptor blocker-(ARB), reduce COVID-19 morbidity and …
antihypertensive angiotensin receptor blocker-(ARB), reduce COVID-19 morbidity and …
Inhalable vaccines: Can they help control pandemics?
The emergence of a new coronavirus presents a huge risk to public health worldwide and
has spread widely amongst the human population. Since its emergence, the severe acute …
has spread widely amongst the human population. Since its emergence, the severe acute …