Giant virus biology and diversity in the era of genome-resolved metagenomics

F Schulz, C Abergel, T Woyke - Nature Reviews Microbiology, 2022 - nature.com
The discovery of giant viruses, with capsids as large as some bacteria, megabase-range
genomes and a variety of traits typically found only in cellular organisms, was one of the …

Virologs, viral mimicry, and virocell metabolism: the expanding scale of cellular functions encoded in the complex genomes of giant viruses

M Moniruzzaman, MP Erazo Garcia… - FEMS microbiology …, 2023 - academic.oup.com
The phylum Nucleocytoviricota includes the largest and most complex viruses known. These
“giant viruses” have a long evolutionary history that dates back to the early diversification of …

Mesophilic and thermophilic viruses are associated with nutrient cycling during hyperthermophilic composting

H Liao, C Liu, C Ai, T Gao, QE Yang, Z Yu… - The ISME …, 2023 - academic.oup.com
While decomposition of organic matter by bacteria plays a major role in nutrient cycling in
terrestrial ecosystems, the significance of viruses remains poorly understood. Here we …

A phylogenomic framework for charting the diversity and evolution of giant viruses

FO Aylward, M Moniruzzaman, AD Ha, EV Koonin - PLoS Biology, 2021 - journals.plos.org
Large DNA viruses of the phylum Nucleocytoviricota have recently emerged as important
members of ecosystems around the globe that challenge traditional views of viral …

Infection strategy and biogeography distinguish cosmopolitan groups of marine jumbo bacteriophages

AR Weinheimer, FO Aylward - The ISME Journal, 2022 - academic.oup.com
Recent research has underscored the immense diversity and key biogeochemical roles of
large DNA viruses in the ocean. Although they are important constituents of marine …

Viral histones: pickpocket's prize or primordial progenitor?

PB Talbert, KJ Armache, S Henikoff - Epigenetics & chromatin, 2022 - Springer
The common histones H2A, H2B, H3, and H4 are the characteristic components of
eukaryotic nucleosomes, which function to wrap DNA and compact the genome as well as to …

Past and present giant viruses diversity explored through permafrost metagenomics

S Rigou, S Santini, C Abergel, JM Claverie… - Nature …, 2022 - nature.com
Giant viruses are abundant in aquatic environments and ecologically important through the
metabolic reprogramming of their hosts. Less is known about giant viruses from soil even …

Giant viruses encode actin-related proteins

V Da Cunha, M Gaia, H Ogata, O Jaillon… - Molecular biology …, 2022 - academic.oup.com
The emergence of the eukaryotic cytoskeleton is a critical yet puzzling step of
eukaryogenesis. Actin and actin-related proteins (ARPs) are ubiquitous components of this …

Metabolic arsenal of giant viruses: Host hijack or self-use?

D Brahim Belhaouari, GA Pires De Souza, DC Lamb… - Elife, 2022 - elifesciences.org
Viruses generally are defined as lacking the fundamental properties of living organisms in
that they do not harbor an energy metabolism system or protein synthesis machinery …

Taxonomic update for giant viruses in the order Imitervirales (phylum Nucleocytoviricota)

FO Aylward, JS Abrahão, CPD Brussaard… - Archives of …, 2023 - Springer
Large DNA viruses in the phylum Nucleocytoviricota, sometimes referred to as “giant
viruses” owing to their large genomes and virions, have been the subject of burgeoning …