Herba Siegesbeckiae: A review on its traditional uses, chemical constituents, pharmacological activities and clinical studies

Q Wang, YY Liang, KW Li, Y Li, FJ Niu, SJ Zhou… - Journal of …, 2021 - Elsevier
Highlights•This is the first review to summarize the studies of traditional uses,
phytochemistry, pharmacology of Herba Siegesbeckiae (HS).•Traditional uses of HS …

Kirenol: A promising bioactive metabolite from siegesbeckia species: A detailed review

SRM Ibrahim, AE Altyar, IA Sindi, DS El-Agamy… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Kirenol (Kr) is an ent-pimarane type diterpenoid
that has been reported from Siegesbeckia orientalis, S. pubescens, and S. glabrescens …

Kirenol, darutoside and hesperidin contribute to the anti-inflammatory and analgesic activities of Siegesbeckia pubescens makino by inhibiting COX-2 expression and …

YS Li, J Zhang, GH Tian, HC Shang, HB Tang - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance The Chinese traditional medicine of Siegesbeckia
pubescens Makino (SM), which has the effect of healing rheumatism and promoting joint …

Multi-omics strategy reveals that Cordyceps sinensis ameliorates sepsis-associated acute kidney injury via reprogramming of mitochondrial energy metabolism and …

L Chen, T Yang, J Wu, G Cheng, M Zhao… - Acta Materia …, 2024 - scienceopen.com
Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional
medicine for the prevention, treatment, and prognostication of various diseases, because of …

Revealing the pharmacological effect and mechanism of darutoside on gouty arthritis by liquid chromatography/mass spectrometry and metabolomics

J Wang, YC Sun - Frontiers in molecular biosciences, 2022 - frontiersin.org
Darutoside is a diterpenoids compound with significant anti-inflammatory activity, however
the pharmacological action and mechanism are still unclear. Metabolomics strategy was …

Exploring the efficacious subfractions and underlying mechanisms of Herba Siegesbeckiae against myocardial ischemia/reperfusion injury via the UCHL5/NLRP3 …

X Wu, H **a, W Li, J Chen, L Zhou, Q Zhang… - Acta Materia …, 2024 - scienceopen.com
Herba Siegesbeckiae (HS) has been traditionally used for managing cardio-and cerebro-
vascular diseases. Our previous study demonstrated that HS ameliorates myocardial …

Diverse diterpenoids and sesquiterpenoids from Siegesbeckia pubescens and their activity against RANKL-induced osteoclastogenesis

Z Sun, Y Zhang, H Zhou, J Xu, Q Gu - Bioorganic Chemistry, 2021 - Elsevier
Phytochemical investigation of the aerial parts of Siegesbeckia pubescens led to seventeen
diterpenoids (1–17) and twelve sesquiterpenoids (18–29). Their structures were varied …

MicroRNA‑502‑3p promotes Mycobacterium tuberculosis survival in macrophages by modulating the inflammatory response by targeting ROCK1

F Liu, Z Dong, Y Lin, H Yang… - Molecular Medicine …, 2021 - spandidos-publications.com
Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M. tuberculosis) infection and
has the highest mortality rate of any single infectious disease worldwide. The aim of the …

Suppressive Effects of Siegesbeckia orientalis Ethanolic Extract on Proliferation and Migration of Hepatocellular Carcinoma Cells through Promoting Oxidative Stress …

TH Chen, CC Chang, JY Houng, TH Chang, YL Chen… - Pharmaceuticals, 2022 - mdpi.com
Previous studies have demonstrated that Siegesbeckia orientalis (SO) has a suppressive
effect on the growth and migration of endometrial and cervical cancer cells. The present …

[HTML][HTML] Comprehensive review of patients with hypercoagulable state in rheumatoid arthritis and strategies to reduce readmission rates: A retrospective cohort study …

Y Li, J Liu, Y Hu, C Cong, Y Chen, F Wang - Medicine, 2024 - journals.lww.com
This study aimed to investigate the effect of traditional Chinese medicine (TCM) intervention
on the risk of readmission and laboratory indicators in patients with rheumatoid arthritis …