Cellular functions of actin-and microtubule-associated septins

ET Spiliotis, K Nakos - Current Biology, 2021 - cell.com
Septins are an integral component of the cytoskeleton, assembling into higher-order
oligomers and filamentous polymers that associate with actin filaments, microtubules and …

Septins: the fourth component of the cytoskeleton

S Mostowy, P Cossart - Nature reviews Molecular cell biology, 2012 - nature.com
Septins belong to a family of proteins that is highly conserved in eukaryotes and is
increasingly recognized as a novel component of the cytoskeleton. All septins are GTP …

Structure-function relationships of the G domain, a canonical switch motif

A Wittinghofer, IR Vetter - Annual review of biochemistry, 2011 - annualreviews.org
GTP-binding (G) proteins constitute a class of P-loop (phosphate-binding loop) proteins that
work as molecular switches between the GDP-bound OFF and the GTP-bound ON state. The …

The state of the septin cytoskeleton from assembly to function

BL Woods, AS Gladfelter - Current opinion in cell biology, 2021 - Elsevier
Septins are conserved guanine nucleotide-binding proteins that polymerize into filaments at
the cell cortex or in association with other cytoskeletal proteins, such as actin or …

The Shigella kinase effector OspG modulates host ubiquitin signaling to escape septin-cage entrapment

W **oeca rosetta
SR Fairclough, Z Chen, E Kramer, Q Zeng, S Young… - Genome biology, 2013 - Springer
Background Metazoan multicellularity is rooted in mechanisms of cell adhesion, signaling,
and differentiation that first evolved in the progenitors of metazoans. To reconstruct the …

Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton

AA Bridges, MS Jentzsch, PW Oakes… - Journal of Cell …, 2016 - rupress.org
Cells change shape in response to diverse environmental and developmental conditions,
creating topologies with micron-scale features. Although individual proteins can sense …