Coronavirus disease (COVID‐19) caused by the novel coronavirus (SARS‐CoV‐2) has
rapidly spread across the globe affecting 213 countries or territories with greater than six …

Senescence is a state of cell cycle arrest that plays an important role in embryogenesis,
wound healing and protection against cancer. Senescent cells also accumulate during …

Ethnopharmacological relevance Pulmonary fibrosis (PF) is a chronic, debilitating and often
lethal lung disorder. Despite the molecular mechanisms of PF are gradually clear with …

Purinergic receptor P2x7 (P2x7R) is a key modulator of liver inflammation and fibrosis. The
present study aimed to investigate the role of P2x7R in hepatic stellate cells activation …

The novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has generated the ongoing coronavirus disease-2019 (COVID-19) pandemic, still with an …

Background Metformin, a commonly used oral antidiabetic agent, is known to possess
pleiotropic antioxidant, anti-inflammatory and anti-fibrotic effects. In this study, we evaluated …

Hirsutella sinensis, the anamorph of Ophiocordyceps sinensis (syn. Cordyceps sinensis), is
a great substitute for precious and rare wild Cordyceps sinensis to effectively treat a variety …

Mesenchymal stem cells (MSCs) are widely considered for treatment of pulmonary fibrosis
based on the anti-inflammatory, antifibrotic, antiapoptotic, and regenerative properties of the …

Introduction Bleomycin (BLM) is a chemotherapeutic agent that is used in the management
of some human cancers such as lymphomas and squamous cell carcinomas. The major …

Most humans depend on sunlight exposure to satisfy their requirements for vitamin D3.
However, the destruction of the ozone layer in the past few decades has increased the risk …