Epidemiological and experimental evidence implicates oestrogens in the aetiology of breast
cancer. Most established risk factors for breast cancer in humans probably act through …

As early as the 1800s, the actions of estrogen have been implicated in the development and
progression of breast cancer. The estrogen receptor (ER) was identified in the late 1950s …

Animal models are powerful tools to analyze the mechanism of the induction of human
breast cancer. Here we report a detailed analysis of mammary tumor progression in one …

Established risk factors for breast cancer explain breast cancer risk only partially. Hence,
there has been interest in evaluating what role environmental chemicals, especially those …

Estrogens have long been recognized as being important for stimulating the growth of a
large proportion of breast cancers. Now it is recognized that estrogen action is mediated by …

Breast cancer is the most common cancer in women and the leading cause of cancer death
among women 35-54 years of age. Rising incidence, increased risk among migrants to …

Since cell proliferation is indispensable for the growth and development of the breast, and
estrogens are considered to play a major role in promoting cell proliferation, while …

Carcinogenesis encompasses 3 closely associated stages: initiation, progression, and
promotion. Phytochemicals are nonnutritive components of plants that are currently being …

Piperidine is an important pharmacophore, a privileged scaffold and an excellent
heterocyclic system in the field of drug discovery which provides numerous opportunities in …

Therapeutic progress in adrenocortical carcinoma (ACC) is severely hampered by its low
incidence. Platinum-based chemotherapies are the most effective cytotoxic treatment …