Background Food safety is a major global public health issue. The majority of traditional
culture-based methods have lengthy detection times, require sophisticated sample …

DNA computing represents a subfield of molecular computing with the potential to become a
significant area of next-generation computation due to the high programmability inherent in …

Riboswitches are ligand-responsive gene-regulatory RNA elements that perform key roles in
maintaining cellular homeostasis. Understanding how riboswitch sensitivity to ligand (EC50) …

Artificial riboswitches responsive to user-defined analytes can be constructed by
successfully inserting in vitro selected aptamers, which bind to the analytes, into …

Although rational genetic engineering is nowadays the favored method for microbial strain
improvement, building up mutant libraries based on directed evolution for improvement is …

As an important branch of biosensors, gene circuit-based biosensors constructed based on
synthetic biology concepts can sense specific substances to be measured and converted …

A large body of work has shown that transcriptional riboswitches function through internal
strand displacement mechanisms that guide the formation of alternative structures which …

The specificity of biological systems makes it possible to develop biosensors targeting
specific metabolites, toxins, and pollutants in complex medical or environmental samples …

In bacteria, where gene transcription and translation occur concurrently, post-transcriptional
regulation is acknowledged to be effective and precise. The 5′ untranslated regions …

Accurate and sensitive monitoring of the concentration change of anti-digoxigenin (Anti-Dig)
antibody is of great importance for diagnosing infectious and immunological diseases …