Comprehensive Profiling and Therapeutic Insights into Differentially Expressed Genes in Hepatocellular Carcinoma
Simple Summary Hepatocellular carcinoma remains crucial due to its high prevalence and
the need for improved understanding and treatment options. This study utilizes extensive …
the need for improved understanding and treatment options. This study utilizes extensive …
Systems-level identification of key transcription factors in immune cell specification
C Liu, K Omilusik, C Toma, NS Kurd… - PLOS Computational …, 2022 - journals.plos.org
Transcription factors (TFs) are crucial for regulating cell differentiation during the
development of the immune system. However, the key TFs for orchestrating the specification …
development of the immune system. However, the key TFs for orchestrating the specification …
High expression of E2F4 is an adverse prognostic factor and related to immune infiltration in oral squamous cell carcinoma
Y Zheng, H Fei - BioMed Research International, 2022 - Wiley Online Library
Background. We aimed to evaluate the prognostic value of E2F4 expression in oral
squamous cell carcinoma (OSCC) and clarify its influence on immune cell infiltration and …
squamous cell carcinoma (OSCC) and clarify its influence on immune cell infiltration and …
Dopamine and dopamine receptor D1 as a novel favourable biomarker for hepatocellular carcinoma
Z Wang, P Wen, B Hu, S Cao, X Shi, W Guo… - Cancer Cell …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) remains one of the most common malignant
tumours worldwide. Therefore, the identification and development of sensitivity-genes as …
tumours worldwide. Therefore, the identification and development of sensitivity-genes as …
Integrative analysis reveals the potential role and prognostic value of GOLM1 in hepatocellular carcinoma
Y Lin, Z He, X Gao, L Lu, C Lu, J Huang… - Oxidative Medicine …, 2022 - Wiley Online Library
Overexpression of Golgi membrane protein 1 (GOLM1) is closely associated with
hepatocellular carcinoma (HCC) vascular invasion. How GOLM1 may be involved in …
hepatocellular carcinoma (HCC) vascular invasion. How GOLM1 may be involved in …
[HTML][HTML] Transcription factor E2F4 facilitates SUMOylation to promote HCC progression through interaction with LIN9
Z Ma, Q Li, W Wang, Z Deng - … Journal of Oncology, 2024 - spandidos-publications.com
SUMOylation plays a crucial role in numerous cellular biological and pathophysiological
processes associated with human disease; however, the mechanisms regulating the genes …
processes associated with human disease; however, the mechanisms regulating the genes …
CDK1-SRC Interaction-Dependent Transcriptional Activation of HSP90AB1 Promotes Antitumor Immunity in Hepatocellular Carcinoma
YJ Zhang, DH Yi - Journal of Proteome Research, 2023 - ACS Publications
This study aimed to analyze multiomics data and construct a regulatory network involving
kinases, transcription factors, and immune genes in hepatocellular carcinoma (HCC) …
kinases, transcription factors, and immune genes in hepatocellular carcinoma (HCC) …
DeepCG: A cell graph model for predicting prognosis in lung adenocarcinoma
Lung cancer is the first leading cause of cancer‐related death in the United States, with lung
adenocarcinoma as the major subtype accounting for 40% of all cases. To improve patient …
adenocarcinoma as the major subtype accounting for 40% of all cases. To improve patient …
Uncovering novel roles of miR-122 in the pathophysiology of the liver: Potential interaction with NRF1 and E2F4 signaling
Simple Summary The microRNA miR-122 plays a crucial role in liver function, but its full
impact on gene regulation and disease mechanisms remains unclear. To better understand …
impact on gene regulation and disease mechanisms remains unclear. To better understand …
[HTML][HTML] Transcriptomic analysis of HPV-positive oesophageal tissue reveals upregulation of genes linked to cell cycle and DNA replication
Human papillomavirus (HPV) is a prevalent sexually transmitted infection, implicated in
various cancers, yet its influence in non-cancerous oesophageal tissue remains unclear …
various cancers, yet its influence in non-cancerous oesophageal tissue remains unclear …