Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application

T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …

Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Beyond traditional biosensors: Recent advances in gold nanoparticles modified electrodes for biosensing applications

G Siciliano, A Alsadig, MS Chiriacò, A Turco… - Talanta, 2024 - Elsevier
Gold nanoparticles (AuNPs) have emerged as powerful tools in the construction of highly
sensitive electrochemical biosensors. Their unique properties, such as the ability to serve as …

Hybridization chain reaction: a versatile molecular tool for biosensing, bioimaging, and biomedicine

S Bi, S Yue, S Zhang - Chemical Society Reviews, 2017 - pubs.rsc.org
Develo** powerful, simple and low-cost DNA amplification techniques is of great
significance to bioanalysis and biomedical research. Thus far, many signal amplification …

Isothermal amplification of nucleic acids

Y Zhao, F Chen, Q Li, L Wang, C Fan - Chemical reviews, 2015 - ACS Publications
Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …

Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

Electrochemical sensors and biosensors based on nanomaterials and nanostructures

C Zhu, G Yang, H Li, D Du, Y Lin - Analytical chemistry, 2015 - ACS Publications
Taking advantage of exceptional attributes, such as being easy-to-operate, economical,
sensitive, portable, and simple-to-construct, in recent decades, considerable attention has …

[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis

M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy

HM Meng, H Liu, H Kuai, R Peng, L Mo… - Chemical Society …, 2016 - pubs.rsc.org
The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …

Rationally engineered nucleic acid architectures for biosensing applications

M **ao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …