Molecular tools to detect alloforms of Aβ and Tau: Implications for multiplexing and multimodal diagnosis of Alzheimer's disease

H Arora, M Ramesh, K Rajasekhar… - Bulletin of the …, 2020‏ - academic.oup.com
The advancements in the field of imaging and diagnostics have been benefitted by the
concurrent expansion of molecular probes space to monitor the diverse biological targets …

Detection of Aβ monomers and oligomers: early diagnosis of Alzheimer's disease

Y Zhou, L Liu, Y Hao, M Xu - Chemistry–An Asian Journal, 2016‏ - Wiley Online Library
Abstract Alzheimer's disease (AD), as the most common progressive neurodegenerative
disorder, is pathologically characterized by deposition of extracellular plaque composed of …

Simple Colorimetric Detection of Amyloid β-peptide (1-40) based on Aggregation of Gold Nanoparticles in the Presence of Copper Ions.

Y Zhou, H Dong, L Liu, M Xu - Small (Weinheim an der Bergstrasse …, 2015‏ - europepmc.org
A simple method for specific colorimetric sensing of Alzheimer's disease related amyloid-β
peptide (Aβ) is developed based on the aggregation of gold nanoparticles in the presence of …

Designing bifunctionalized gold nanoparticle for colorimetric detection of Pb2+ under physiological condition

D Zhu, X Li, X Liu, J Wang, Z Wang - Biosensors and Bioelectronics, 2012‏ - Elsevier
In the present work, a kind of peptide functionalized gold nanoparticle (AuNP) has been
synthesized and employed for colorimetric detection of Pb2+ in both aqueous solution and …

Resonance light scattering as a powerful tool for sensitive detection ofβ-amyloid peptide by gold nanoparticle probes

C Wang, D Liu, Z Wang - Chemical Communications, 2011‏ - pubs.rsc.org
A novel biosensing strategy has been developed for sensitive detection of β-amyloid 1–42
(Aβ1–42) down to the ng mL− 1 level in both aqueous solution and diluted human plasma …

Preparation and application of thionin-bridged graphene–gold nanoparticle nanohybrids

Z Zhu, L Ma, M Su, D Liu, Z Wang - Journal of Materials Chemistry B, 2013‏ - pubs.rsc.org
A universal approach for controllable assembly of gold nanoparticles (AuNPs) on chemically
reduced graphene oxide (rGO) is presented. AuNPs were conjugated to thionin (TH) …

A fast, highly selective and sensitive dansyl-based fluorescent sensor for copper (II) ions and its imaging application in living cells

M Zhou, X Wang, K Huang, Y Huang, S Hu, W Zeng - Tetrahedron Letters, 2017‏ - Elsevier
Since the copper ions (Cu 2+) play a fatal role in many foundational physiological
processes, it is important to develop a simple, highly sensitive and selective sensor for Cu …

Visual detection of copper (II) ions in blood samples by controlling the leaching of protein-capped gold nanoparticles

YF Lee, TW Deng, WJ Chiu, TY Wei, P Roy, CC Huang - Analyst, 2012‏ - pubs.rsc.org
We have developed a simple, low-cost, paper-based probe for the selective colorimetric
detection of copper ions (Cu2+) in aqueous solutions. The bovine serum albumin (BSA) …

Sensitive colorimetric detection of lysozyme in human serum using peptide-capped gold nanoparticles

H Huang, Q Zhang, J Luo, Y Zhao - Analytical Methods, 2012‏ - pubs.rsc.org
This paper shows a simple, robust and sensitive colorimetric platform for lysozyme detection.
This method is based on the fact that Cys-Ala-Leu-Asn-Asn (CALNN)-capped gold …

Rational design of an anchoring peptide for high-efficiency and quantitative modification of peptides and DNA strands on gold nanoparticles

XY Li, FY Feng, XD Zhou, JM Hu - Nanoscale, 2018‏ - pubs.rsc.org
The pentapeptide Cys-Ala-Leu-Asn-Asn (CALNN) could stabilize gold nanoparticles
(AuNPs), most of which serve as anchoring blocks for various bioanalyses by introducing …