Neuroprosthetics: from sensorimotor to cognitive disorders

A Gupta, N Vardalakis, FB Wagner - Communications biology, 2023 - nature.com
Neuroprosthetics is a multidisciplinary field at the interface between neurosciences and
biomedical engineering, which aims at replacing or modulating parts of the nervous system …

[HTML][HTML] Brain (re) organisation following amputation: Implications for phantom limb pain

TR Makin, H Flor - Neuroimage, 2020 - Elsevier
Following arm amputation the region that represented the missing hand in primary
somatosensory cortex (S1) becomes deprived of its primary input, resulting in changed …

Low-threshold, high-resolution, chronically stable intracortical microstimulation by ultraflexible electrodes

R Lycke, R Kim, P Zolotavin, J Montes, Y Sun… - Cell reports, 2023 - cell.com
Intracortical microstimulation (ICMS) enables applications ranging from neuroprosthetics to
causal circuit manipulations. However, the resolution, efficacy, and chronic stability of …

[HTML][HTML] High-density single-unit human cortical recordings using the Neuropixels probe

JE Chung, KK Sellers, MK Leonard, L Gwilliams, D Xu… - Neuron, 2022 - cell.com
The action potential is a fundamental unit of neural computation. Even though significant
advances have been made in recording large numbers of individual neurons in animal …

The Argo: a high channel count recording system for neural recording in vivo

K Sahasrabuddhe, AA Khan, AP Singh… - Journal of neural …, 2021 - iopscience.iop.org
Objective. Decoding neural activity has been limited by the lack of tools available to record
from large numbers of neurons across multiple cortical regions simultaneously with high …

Perception of microstimulation frequency in human somatosensory cortex

CL Hughes, SN Flesher, JM Weiss, M Boninger… - Elife, 2021 - elifesciences.org
Microstimulation in the somatosensory cortex can evoke artificial tactile percepts and can be
incorporated into bidirectional brain–computer interfaces (BCIs) to restore function after …

Modulating brain activity with invasive brain–computer interface: A narrative review

ZP Zhao, C Nie, CT Jiang, SH Cao, KX Tian, S Yu… - Brain sciences, 2023 - mdpi.com
Brain-computer interface (BCI) can be used as a real-time bidirectional information gateway
between the brain and machines. In particular, rapid progress in invasive BCI, propelled by …

Neuromorphic hardware for somatosensory neuroprostheses

E Donati, G Valle - Nature Communications, 2024 - nature.com
In individuals with sensory-motor impairments, missing limb functions can be restored using
neuroprosthetic devices that directly interface with the nervous system. However, restoring …

Multifaceted understanding of human nerve implants to design optimized electrodes for bioelectronics

G Valle, G Aiello, F Ciotti, P Cvancara, T Martinovic… - Biomaterials, 2022 - Elsevier
Bioelectronic medicine is a promising venue for treatment of disabilities using implantable
neural interfaces. Peripheral neurostimulation of residual nerves recently enabled multiple …

Explant analysis of Utah electrode arrays implanted in human cortex for brain-computer-interfaces

K Woeppel, C Hughes, AJ Herrera, JR Eles… - … in Bioengineering and …, 2021 - frontiersin.org
Brain-computer interfaces are being developed to restore movement for people living with
paralysis due to injury or disease. Although the therapeutic potential is great, long-term …