Klebsiella pneumoniae is among the most common antibiotic-resistant pathogens causing
nosocomial infections. Additionally, it is a leading cause of neonatal sepsis and childhood …

Phage therapy has been overshadowed by antibiotics for decades. However, it is being
revisited as a powerful approach against antimicrobial-resistant bacteria. As bacterial …

CRISPR-Cas systems can be utilized as programmable-spectrum antimicrobials to combat
bacterial infections. However, how CRISPR nucleases perform as antimicrobials across …

Bacteriophages play key roles in bacterial ecology and evolution and are potential
antimicrobials. However, the determinants of phage-host specificity remain elusive. Here, we …

Colonisation by bacterial pathogens typically precedes invasive infection and seeds
transmission. Thus, effective decolonisation strategies are urgently needed. The literature …

Klebsiella pneumoniae are a leading cause of healthcare-associated infections worldwide.
In particular, strains expressing extended-spectrum β-lactamases (ESBLs) and …

One of the most common bacteria that cause nosocomial infections is Klebsiella pneumonia
(K. pneumoniae), especially in patients who are very sick and admitted to the intensive care …

Highly encapsulated hypervirulent Klebsiella pneumoniae (hvKp) causes severe infections.
Bacteriophage therapy, an antibiotic alternative, effectively treats bacterial infections. Phage …

Antimicrobial resistance is a major threat to human and animal health and accounted for up
to 4.5 million deaths worldwide in 2019. Asymptomatic colonization of the digestive tract by …

Bacteriophages largely impact bacterial communities via lysis, gene transfer, and metabolic
reprogramming and thus are increasingly thought to alter nutrient and energy cycling across …