Over recent decades, a growing body of literature has validated the use of bacteriophages
for therapy and prophylaxis in the war against drug-resistant bacteria. Today, much more is …

Resistance to drug treatment is an important hurdle in the therapy of many brain disorders,
including brain cancer, epilepsy, schizophrenia, depression and infection of the brain with …

The differential transcriptional response of Mycobacterium tuberculosis to drugs and growth-
inhibitory conditions was monitored to generate a data set of 430 microarray profiles …

▪ Abstract Modern chemotherapy has played a major role in our control of tuberculosis. Yet
tuberculosis still remains a leading infectious disease worldwide, largely owing to …

Antimicrobial resistance is one of the most serious public health issues facing humans since
the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of …

ABSTRACT Type II DNA methyltransferases (MTases) are enzymes found ubiquitously in
the prokaryotic world, where they play important roles in several cellular processes, such as …

Phenothiazines have been used in many areas of medicine, mainly in psychopharmacology.
These compounds are able to effectively inhibit dopamine, histamine, serotonin …

Mycobacterium tuberculosis (Mtb) is an obligate aerobe that is capable of long-term
persistence under conditions of low oxygen tension. Analysis of the Mtb genome predicts the …

AIMS: Tuberculosis and mental illness share common risk factors including homelessness,
HIV positive serology, alcohol/substance abuse and migrant status leading to frequent …

Therapeutic options for tuberculosis (TB) are limited and notoriously ineffective despite the
wide variety of potent antibiotics available for treating other bacterial infections. We …