Vascular cell adhesion molecule‐1 (VCAM‐1) first attracted attention more than two
decades ago as endothelial adhesion receptor with key function for leukocyte recruitment in …

The principal targets for anti-chemokine therapy in inflammatory bowel disease (IBD) have
been the receptors CCR9 and CXCR3 and their respective ligands CCL25 and CXCL10 …

Chemokine is a structure-related protein with a relatively small molecular weight, which can
target cells to chemotaxis and promote inflammatory response. Inflammation plays an …

Tumor-infiltrating lymphocytes (TILs) are important prognostic factors in cancer progression
and key players in cancer immunotherapy. Although γδ T lymphocytes can target a diversity …

Gamma–delta (γδ) T cells play an essential role in allergic diseases and have emerged as a
potential treatment target in recent decades. To clarify the effects of γδ T cells on atopic …

Gamma–delta T cells (γδ T cells) are an unique group of lymphocytes and play an important
role in bridging the gap between innate and adaptive immune systems under homeostatic …

Although considerable efforts have been conducted to diagnose, improve, and treat cancer
in the past few decades, existing therapeutic options are insufficient, as mortality and …

Background Periodontitis is a chronic inflammatory disease triggered by the host immune
response. Epigenetic modifications also affect the immune response. We assessed CpG …

In comparison to conventional αβT cells, γδT cells are considered as specialized T cells
based on their contributions in regulating immune response. γδT cells sense early …

Preprogrammed IL-17-producing γδ T cells constitute a poorly understood class of
lymphocytes that express rearranged antigen receptors but appear to make little use of …