Alcohol use disorder (AUD) is a highly prevalent, comorbid, and disabling disorder. The
underlying mechanism of ethanol neurotoxicity and the involvement of oxidative stress is still …

Telomeres are nucleoprotein structures that cap the end of each chromosome arm and
function to maintain genome stability. The length of telomeres is known to shorten with each …

Background Human aging is associated with DNA methylation changes at specific sites in
the genome. These epigenetic modifications may be used to track donor age for forensic …

Many psychiatric illnesses are associated with early mortality and with an increased risk of
develo** physical diseases that are more typically seen in the elderly. Moreover, certain …

In the past decade, the growing field of telomere science has opened exciting new avenues
for understanding the cellular and molecular substrates of stress and stress-related aging …

The purpose of this study was to examine the association between socioeconomic status
(SES) and leukocyte telomere length (LTL)–a marker of cell aging that has been linked to …

The long-term sequelae of adverse early-life experiences have long been a focus in
psychiatry, with a historic neurobiological emphasis on physiological systems that are …

Background Telomere shortening and alterations of mitochondrial biogenesis are involved
in cellular aging. Childhood adversity is associated with telomere shortening, and several …

Background Even before the onset of age-related diseases, obesity might be a contributing
factor to the cumulative burden of oxidative stress and chronic inflammation throughout the …

Older people are at an increased risk of develo** respiratory diseases such as chronic
obstructive pulmonary diseases, asthma, idiopathic pulmonary fibrosis or lung infections …