Restoring sensorimotor function through intracortical interfaces: progress and looming challenges

SJ Bensmaia, LE Miller - Nature Reviews Neuroscience, 2014 - nature.com
The loss of a limb or paralysis resulting from spinal cord injury has devastating
consequences on quality of life. One approach to restoring lost sensory and motor abilities in …

Constraints on somatotopic organization in the primary motor cortex

MH Schieber - Journal of neurophysiology, 2001 - journals.physiology.org
Since the 1870s, the primary motor cortex (M1) has been known to have a somatotopic
organization, with different regions of cortex participating in control of face, arm, and leg …

Hand function: peripheral and central constraints on performance

MH Schieber, M Santello - Journal of applied physiology, 2004 - journals.physiology.org
The hand is one of the most fascinating and sophisticated biological motor systems. The
complex biomechanical and neural architecture of the hand poses challenging questions for …

Cortical mechanism for the visual guidance of hand gras** movements in the monkey: A reversible inactivation study

L Fogassi, V Gallese, G Buccino, L Craighero, L Fadiga… - Brain, 2001 - academic.oup.com
Picking up an object requires two basic motor operations: reaching and gras**.
Neurophysiological studies in monkeys have suggested that the visuomotor transformations …

Dissociating the role of ventral and dorsal premotor cortex in precision gras**

M Davare, M Andres, G Cosnard… - Journal of …, 2006 - Soc Neuroscience
Small-object manipulation is essential in numerous human activities, although its neural
bases are still essentially unknown. Recent functional imaging studies have shown that …

Correlates of human handedness in primary motor cortex: a review and hypothesis

G Hammond - Neuroscience & biobehavioral reviews, 2002 - Elsevier
A review of the research on anatomical and functional asymmetries in human primary motor
cortex suggests that the area of hand representation is greater in the dominant than in the …

Microstimulation of human somatosensory cortex evokes task-dependent, spatially patterned responses in motor cortex

ND Shelchkova, JE Downey, CM Greenspon… - Nature …, 2023 - nature.com
The primary motor (M1) and somatosensory (S1) cortices play critical roles in motor control
but the signaling between these structures is poorly understood. To fill this gap, we recorded …

Transient deactivation of dorsal premotor cortex or parietal area 5 impairs feedback control of the limb in macaques

T Takei, SG Lomber, DJ Cook, SH Scott - Current Biology, 2021 - cell.com
We can generate goal-directed motor corrections with surprising speed, but their neural
basis is poorly understood. Here, we show that temporary cooling of dorsal premotor cortex …

Differential impairment of individuated finger movements in humans after damage to the motor cortex or the corticospinal tract

CE Lang, MH Schieber - Journal of neurophysiology, 2003 - journals.physiology.org
The purpose of this study was to quantify the long-term loss of independent finger
movements in humans with lesions relatively restricted to motor cortex or corticospinal tract …

Low-frequency stimulation enhances ensemble co-firing and dexterity after stroke

P Khanna, D Totten, L Novik, J Roberts, RJ Morecraft… - Cell, 2021 - cell.com
Electrical stimulation is a promising tool for modulating brain networks. However, it is
unclear how stimulation interacts with neural patterns underlying behavior. Specifically, how …